113426

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 5002235..5002790 Replicon chromosome
Accession NZ_CP033230
Organism Sphingobium yanoikuyae strain SJTF8

Toxin (Protein)


Gene name parE Uniprot ID A0A3G2UYY3
Locus tag EBF16_RS27530 Protein ID WP_037510634.1
Coordinates 5002482..5002790 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A085K2G2
Locus tag EBF16_RS27525 Protein ID WP_037510637.1
Coordinates 5002235..5002480 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBF16_RS27505 4997564..4998277 + 714 WP_037510644.1 SDR family oxidoreductase -
EBF16_RS27510 4998450..4999640 + 1191 WP_037510759.1 chromate efflux transporter -
EBF16_RS27515 4999728..5000714 + 987 WP_037510642.1 phosphatase PAP2 family protein -
EBF16_RS27520 5000711..5002087 - 1377 WP_037510640.1 amidohydrolase -
EBF16_RS27525 5002235..5002480 + 246 WP_037510637.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
EBF16_RS27530 5002482..5002790 + 309 WP_037510634.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EBF16_RS27535 5002797..5004311 - 1515 WP_037510632.1 peptidase S10 -
EBF16_RS27540 5004378..5005655 - 1278 WP_037510757.1 MFS transporter -
EBF16_RS27545 5005805..5007202 - 1398 WP_037510630.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-93)

Antitoxin

Antitoxin ParD

(6-64)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 12016.83 Da        Isoelectric Point: 7.3190

>T113426 WP_037510634.1 NZ_CP033230:5002482-5002790 [Sphingobium yanoikuyae]
MVRYRLTRAASDDIMAIFVDGVERFGLLQADLYHAGLAAAFERIAEYPFAVRLREEIVPPVRVRRFRAHLILYDLVEENR
PLILRVRHGREDWQAREEGPDR

Download         Length: 309 bp

>T113426 NZ_CP033230:5002482-5002790 [Sphingobium yanoikuyae]
ATGGTGCGCTATCGTCTGACCCGTGCGGCGTCGGACGATATTATGGCGATTTTCGTGGATGGTGTCGAACGGTTCGGGCT
GCTGCAGGCCGACCTCTACCATGCGGGATTGGCGGCGGCCTTCGAACGGATTGCGGAATACCCCTTCGCGGTGCGACTGC
GTGAGGAGATCGTGCCGCCGGTGCGGGTGCGCCGCTTTCGAGCGCATCTGATTCTCTATGACCTGGTCGAGGAGAACCGG
CCCCTCATCCTGCGCGTCCGCCATGGTCGGGAAGACTGGCAGGCGCGGGAGGAAGGGCCGGATCGATAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9214.36 Da        Isoelectric Point: 4.7824

>AT113426 WP_037510637.1 NZ_CP033230:5002235-5002480 [Sphingobium yanoikuyae]
MATMNISLPDPMKNWVEAQSATGRYSNASDYVRDLIRRDQERQAKIAHMQMLVDEGREGGISDETMDDIRERALKQAGLQ
C

Download         Length: 246 bp

>AT113426 NZ_CP033230:5002235-5002480 [Sphingobium yanoikuyae]
ATGGCGACGATGAATATTTCCCTGCCCGATCCGATGAAGAACTGGGTAGAGGCGCAATCCGCGACCGGACGATACAGCAA
TGCGAGCGACTATGTGCGCGACCTGATCCGCCGTGATCAGGAGCGACAGGCGAAGATTGCCCATATGCAAATGCTGGTCG
ATGAAGGCCGGGAAGGCGGGATCAGCGACGAGACGATGGACGATATCCGCGAGCGGGCGTTGAAGCAGGCCGGGCTGCAG
TGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2UYY3

Antitoxin

Source ID Structure
AlphaFold DB A0A085K2G2

References