113423

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 2129782..2130239 Replicon chromosome
Accession NZ_CP033230
Organism Sphingobium yanoikuyae strain SJTF8

Toxin (Protein)


Gene name relE Uniprot ID A0A085K038
Locus tag EBF16_RS13750 Protein ID WP_037512240.1
Coordinates 2129964..2130239 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A085K037
Locus tag EBF16_RS13745 Protein ID WP_037512238.1
Coordinates 2129782..2129964 (+) Length 61 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBF16_RS13740 2125539..2128454 + 2916 WP_037512236.1 excinuclease ABC subunit UvrA -
EBF16_RS28680 2128458..2129741 + 1284 WP_153039464.1 hypothetical protein -
EBF16_RS13745 2129782..2129964 + 183 WP_037512238.1 hypothetical protein Antitoxin
EBF16_RS13750 2129964..2130239 + 276 WP_037512240.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
EBF16_RS13755 2130527..2131717 + 1191 WP_037512243.1 hypothetical protein -
EBF16_RS13760 2131829..2132044 + 216 WP_037512246.1 cold-shock protein -
EBF16_RS13765 2132119..2132721 - 603 WP_122129772.1 hypothetical protein -
EBF16_RS13770 2132858..2133064 + 207 WP_010336653.1 hypothetical protein -
EBF16_RS13775 2133259..2133627 + 369 WP_051156876.1 glycine zipper 2TM domain-containing protein -
EBF16_RS13780 2133685..2134617 - 933 WP_037512249.1 FAD-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10740.28 Da        Isoelectric Point: 9.4764

>T113423 WP_037512240.1 NZ_CP033230:2129964-2130239 [Sphingobium yanoikuyae]
MPHVIWRERAREDVRNIIDYISNRNPTAALRLTDLFAHVAEQLVYHPHMHRSGRVPDTREAIVTPNYILVYRVSAEAIEI
LNVKHTRQQYP

Download         Length: 276 bp

>T113423 NZ_CP033230:2129964-2130239 [Sphingobium yanoikuyae]
ATGCCACACGTCATCTGGCGCGAGAGAGCGCGGGAGGACGTGCGCAATATCATCGACTATATTTCTAACCGCAATCCAAC
GGCCGCGCTGCGCCTGACCGATCTGTTCGCTCATGTCGCCGAACAATTGGTCTATCATCCCCATATGCACCGCAGCGGGC
GCGTTCCCGACACGCGCGAAGCCATCGTCACGCCCAACTATATCCTCGTCTACCGGGTCAGTGCCGAAGCGATCGAAATC
CTGAACGTCAAGCACACGCGCCAGCAATATCCCTGA

Antitoxin


Download         Length: 61 a.a.        Molecular weight: 6677.54 Da        Isoelectric Point: 4.5183

>AT113423 WP_037512238.1 NZ_CP033230:2129782-2129964 [Sphingobium yanoikuyae]
MTKLTPIESEFATTEEAAAYDAWFKAEVEASMADPRPGVPHDQVMAELRAIIDAKKARRD

Download         Length: 183 bp

>AT113423 NZ_CP033230:2129782-2129964 [Sphingobium yanoikuyae]
ATGACGAAGCTCACGCCCATCGAGTCCGAATTTGCGACGACCGAGGAGGCCGCCGCCTATGACGCCTGGTTCAAGGCAGA
GGTTGAGGCGAGCATGGCCGATCCCCGGCCGGGTGTGCCGCACGACCAGGTGATGGCCGAATTGCGCGCGATCATCGACG
CCAAGAAGGCCCGGCGGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A085K038

Antitoxin

Source ID Structure
AlphaFold DB A0A085K037

References