Detailed information of TA system TA113389

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 1596892..1597448
• Replicon: chromosome
• Accession: NZ_CP033201
• Organism: Xanthomonas oryzae pv. oryzae strain BXO1

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: BXO1_RS07870
• Protein ID: WP_229001948.1
• Coordinates: 1596892..1597143 (-)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: BXO1_RS07875
• Protein ID: WP_011408759.1
• Coordinates: 1597170..1597448 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BXO1_RS07820 (BXO1_007805)	1592662..1593753	+	1092	WP_041182166.1	ribonuclease D	-
BXO1_RS07825 (BXO1_007810)	1593829..1594166	-	338	Protein_1422	ATP-dependent DNA ligase	-
BXO1_RS07835 (BXO1_007820)	1594448..1594624	-	177	Protein_1423	DUF3606 domain-containing protein	-
BXO1_RS07840 (BXO1_007825)	1594846..1595247	+	402	WP_011259345.1	H-NS family nucleoid-associated regulatory protein	-
BXO1_RS07855 (BXO1_007840)	1595775..1595894	-	120	Protein_1425	IS3 family transposase	-
BXO1_RS07860 (BXO1_007845)	1596111..1596365	-	255	WP_223293127.1	hypothetical protein	-
BXO1_RS25635	1596434..1596631	-	198	WP_004541336.1	hypothetical protein	-
BXO1_RS07870 (BXO1_007855)	1596892..1597143	-	252	WP_229001948.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BXO1_RS07875 (BXO1_007860)	1597170..1597448	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
BXO1_RS07880 (BXO1_007865)	1597644..1598030	-	387	WP_205421001.1	hypothetical protein	-
BXO1_RS07890 (BXO1_007875)	1598894..1600078	-	1185	WP_117231633.1	IS256 family transposase	-
BXO1_RS07900 (BXO1_007885)	1600659..1601624	+	966	WP_109181970.1	IS1595-like element ISXo5 family transposase	-
BXO1_RS07905 (BXO1_007890)	1601774..1602331	+	558	WP_011259349.1	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-81)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9603.92 Da
• Isoelectric Point: 9.9718

>T113389 WP_229001948.1 NZ_CP033201:c1597143-1596892 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Nucleotide

• Length: 252 bp

>T113389 NZ_CP033201:c1597143-1596892 [Xanthomonas oryzae pv. oryzae]
ATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGATGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGT
CCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAGAAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATT
TTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGGGATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAA
GCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT113389 WP_011408759.1 NZ_CP033201:c1597448-1597170 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT113389 NZ_CP033201:c1597448-1597170 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2