Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 1442041..1442556 Replicon chromosome
Accession NZ_CP033200
Organism Micrococcus luteus strain SA211

Toxin (Protein)


Gene name relE Uniprot ID A0A031HZL4
Locus tag FMM_RS06570 Protein ID WP_036316391.1
Coordinates 1442041..1442295 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID D3LMN2
Locus tag FMM_RS06575 Protein ID WP_002855277.1
Coordinates 1442296..1442556 (-) Length 87 a.a.

Genomic Context

FMM_RS06550FMM_RS06555FMM_RS06560FMM_RS06540FMM_RS06545FMM_RS06565FMM_RS06570FMM_RS06575FMM_RS11475FMM_RS06585
Location: 1439383..1440108 (726 bp)
Type: Others
Protein ID: WP_178329127.1
Location: 1440105..1440647 (543 bp)
Type: Others
Protein ID: WP_036316394.1
Location: 1440647..1441429 (783 bp)
Type: Others
Protein ID: WP_036316393.1
Location: 1437739..1438436 (698 bp)
Type: Others
Protein ID: Protein_1264
Location: 1438912..1439145 (234 bp)
Type: Others
Protein ID: Protein_1265
Location: 1441473..1442039 (567 bp)
Type: Others
Protein ID: WP_036316392.1
Location: 1442041..1442295 (255 bp)
Type: Toxin
Protein ID: WP_036316391.1
Location: 1442296..1442556 (261 bp)
Type: Antitoxin
Protein ID: WP_002855277.1
Location: 1444564..1446411 (1848 bp)
Type: Others
Protein ID: WP_189338143.1
Location: 1446422..1447507 (1086 bp)
Type: Others
Protein ID: WP_122054482.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FMM_RS065401437739..1438436-698Protein_1264aquaporin Z-
FMM_RS065451438912..1439145-234Protein_1265hypothetical protein-
FMM_RS065501439383..1440108+726WP_178329127.1MSMEG_4193 family putative phosphomutase-
FMM_RS065551440105..1440647+543WP_036316394.1DUF3090 domain-containing protein-
FMM_RS065601440647..1441429+783WP_036316393.1SCO1664 family protein-
FMM_RS065651441473..1442039-567WP_036316392.1mismatch-specific DNA-glycosylase-
FMM_RS065701442041..1442295-255WP_036316391.1Txe/YoeB family addiction module toxinToxin
FMM_RS065751442296..1442556-261WP_002855277.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
FMM_RS114751444564..1446411-1848WP_189338143.1hypothetical protein-
FMM_RS065851446422..1447507-1086WP_122054482.1redox-regulated ATPase YchF-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(3-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9943.23 Da        Isoelectric Point: 6.7245

>T113388 WP_036316391.1 NZ_CP033200:c1442295-1442041 [Micrococcus luteus]
VRLVWDRSAWEDYTHWQTTDRKVLTRVNTLIDAALRDPFEGIGKPEQLKYGAAGAWSRRITEEHRLVYLVDGEDLIILQA
RYHY

Download         Length: 255 bp

>T113388 NZ_CP033200:c1442295-1442041 [Micrococcus luteus]
GTGCGCCTCGTGTGGGACCGCTCCGCCTGGGAGGACTACACGCACTGGCAGACCACGGACCGCAAGGTCCTCACACGGGT
CAACACCCTCATCGACGCCGCCCTGCGTGATCCCTTCGAGGGGATCGGCAAGCCCGAGCAGCTGAAGTACGGCGCGGCCG
GGGCATGGTCCCGGCGGATCACGGAGGAGCACAGGCTCGTCTACCTCGTCGACGGCGAGGACCTGATCATCCTCCAGGCG
AGGTATCACTACTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9579.71 Da        Isoelectric Point: 4.8359

>AT113388 WP_002855277.1 NZ_CP033200:c1442556-1442296 [Micrococcus luteus]
MSISASEARKTLFPLIERVNADRDAVEIVSRKGNAVLMPADEYAAWQETAYLFRSPANARRLLDAYERARAGSVEEHALD
RLDGDA

Download         Length: 261 bp

>AT113388 NZ_CP033200:c1442556-1442296 [Micrococcus luteus]
ATGTCCATCAGTGCCAGTGAAGCCCGCAAGACCCTGTTCCCGCTCATCGAGCGAGTGAATGCGGACCGCGACGCCGTCGA
GATCGTCTCCCGCAAGGGCAACGCCGTTCTCATGCCCGCGGACGAGTACGCCGCCTGGCAGGAGACCGCCTACCTGTTCC
GCTCCCCGGCCAACGCCCGACGGCTGCTGGACGCCTACGAGCGCGCCCGCGCAGGGAGCGTTGAGGAGCACGCCCTGGAT
CGCCTGGACGGGGACGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A031HZL4

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A031HW70

References