Detailed information of TA system TA113380

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2724162..2724718
• Replicon: chromosome
• Accession: NZ_CP033196
• Organism: Xanthomonas oryzae pv. oryzae strain AUST2013

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: EBA17_RS13740
• Protein ID: WP_027703932.1
• Coordinates: 2724162..2724452 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: EBA17_RS13745
• Protein ID: WP_011408759.1
• Coordinates: 2724440..2724718 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EBA17_RS13690	2719932..2721023	+	1092	WP_041182166.1	ribonuclease D	-
EBA17_RS13695	2721099..2721436	-	338	Protein_2478	ATP-dependent DNA ligase	-
EBA17_RS24915	2721496..2721702	-	207	Protein_2479	hypothetical protein	-
EBA17_RS13705	2721718..2721894	-	177	Protein_2480	DUF3606 domain-containing protein	-
EBA17_RS13710	2722116..2722517	+	402	WP_011259345.1	H-NS histone family protein	-
EBA17_RS13730	2723381..2723560	-	180	WP_015463309.1	hypothetical protein	-
EBA17_RS25170	2723704..2723901	-	198	WP_004541336.1	hypothetical protein	-
EBA17_RS13740	2724162..2724452	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EBA17_RS13745	2724440..2724718	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
EBA17_RS25175	2724799..2725002	-	204	WP_199285669.1	hypothetical protein	-
EBA17_RS25180	2724914..2725258	-	345	WP_199285675.1	hypothetical protein	-
EBA17_RS13755	2725203..2725403	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
EBA17_RS13760	2726164..2727348	-	1185	WP_011408760.1	IS256 family transposase	-
EBA17_RS13770	2727929..2728894	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
EBA17_RS13775	2728996..2729601	+	606	Protein_2491	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T113380 WP_027703932.1 NZ_CP033196:c2724452-2724162 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T113380 NZ_CP033196:c2724452-2724162 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT113380 WP_011408759.1 NZ_CP033196:c2724718-2724440 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT113380 NZ_CP033196:c2724718-2724440 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2