113377

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4734398..4734748 Replicon chromosome
Accession NZ_CP033194
Organism Xanthomonas oryzae pv. oryzae strain CIAT

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag EBA18_RS23140 Protein ID WP_011257368.1
Coordinates 4734398..4734532 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag EBA18_RS23145 Protein ID WP_011407410.1
Coordinates 4734596..4734748 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBA18_RS23125 4731412..4732434 - 1023 WP_075239893.1 MBL fold metallo-hydrolase -
EBA18_RS23130 4732487..4733776 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
EBA18_RS23135 4733945..4734154 - 210 WP_011407411.1 CsbD family protein -
EBA18_RS23140 4734398..4734532 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
EBA18_RS23145 4734596..4734748 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
EBA18_RS23150 4734856..4735779 - 924 WP_011407409.1 arginase -
EBA18_RS23155 4736101..4736775 + 675 WP_011257366.1 hypothetical protein -
EBA18_RS23160 4736772..4737011 + 240 WP_011257365.1 hypothetical protein -
EBA18_RS23165 4737018..4737314 + 297 WP_012446308.1 hypothetical protein -
EBA18_RS23175 4737794..4738477 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T113377 WP_011257368.1 NZ_CP033194:c4734532-4734398 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T113377 NZ_CP033194:c4734532-4734398 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT113377 WP_011407410.1 NZ_CP033194:c4734748-4734596 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT113377 NZ_CP033194:c4734748-4734596 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References