Detailed information of TA system TA113370

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2931673..2932229
• Replicon: chromosome
• Accession: NZ_CP033193
• Organism: Xanthomonas oryzae pv. oryzae strain JW11089

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: EBA19_RS14735
• Protein ID: WP_027703932.1
• Coordinates: 2931673..2931963 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: EBA19_RS14740
• Protein ID: WP_011408759.1
• Coordinates: 2931951..2932229 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EBA19_RS14685	2927443..2928534	+	1092	WP_041182166.1	ribonuclease D	-
EBA19_RS14690	2928610..2928947	-	338	Protein_2640	ATP-dependent DNA ligase	-
EBA19_RS25295	2929007..2929213	-	207	Protein_2641	hypothetical protein	-
EBA19_RS14700	2929229..2929405	-	177	Protein_2642	DUF3606 domain-containing protein	-
EBA19_RS14705	2929627..2930028	+	402	WP_011259345.1	H-NS histone family protein	-
EBA19_RS14715	2930353..2930557	-	205	Protein_2644	kfra protein	-
EBA19_RS14725	2930892..2931071	-	180	WP_015463309.1	hypothetical protein	-
EBA19_RS14730	2931342..2931670	-	329	Protein_2646	hypothetical protein	-
EBA19_RS14735	2931673..2931963	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EBA19_RS14740	2931951..2932229	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
EBA19_RS14745	2932310..2932742	-	433	Protein_2649	relaxase	-
EBA19_RS14750	2932714..2932914	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
EBA19_RS14755	2933675..2934859	-	1185	WP_011408397.1	IS256 family transposase	-
EBA19_RS14765	2935024..2935215	+	192	Protein_2652	transposase	-
EBA19_RS14770	2935304..2936269	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
EBA19_RS14775	2936371..2936976	+	606	Protein_2654	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T113370 WP_027703932.1 NZ_CP033193:c2931963-2931673 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T113370 NZ_CP033193:c2931963-2931673 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT113370 WP_011408759.1 NZ_CP033193:c2932229-2931951 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT113370 NZ_CP033193:c2932229-2931951 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2