Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4748725..4749075 Replicon chromosome
Accession NZ_CP033192
Organism Xanthomonas oryzae pv. oryzae strain NX0260

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag EBA21_RS23265 Protein ID WP_011257368.1
Coordinates 4748725..4748859 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag EBA21_RS23270 Protein ID WP_011407410.1
Coordinates 4748923..4749075 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBA21_RS23250 4745739..4746761 - 1023 WP_075239893.1 MBL fold metallo-hydrolase -
EBA21_RS23255 4746814..4748103 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
EBA21_RS23260 4748272..4748481 - 210 WP_011407411.1 CsbD family protein -
EBA21_RS23265 4748725..4748859 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
EBA21_RS23270 4748923..4749075 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
EBA21_RS23275 4749183..4750106 - 924 WP_011407409.1 arginase -
EBA21_RS23280 4750428..4751102 + 675 WP_011257366.1 hypothetical protein -
EBA21_RS23285 4751099..4751338 + 240 WP_011257365.1 hypothetical protein -
EBA21_RS23290 4751345..4751641 + 297 WP_012446308.1 hypothetical protein -
EBA21_RS23300 4752121..4752804 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T113368 WP_011257368.1 NZ_CP033192:c4748859-4748725 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T113368 NZ_CP033192:c4748859-4748725 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT113368 WP_011407410.1 NZ_CP033192:c4749075-4748923 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT113368 NZ_CP033192:c4749075-4748923 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References