Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3327542..3329061 Replicon chromosome
Accession NZ_CP033191
Organism Xanthomonas oryzae pv. oryzae strain PXO364

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag EBA22_RS16430 Protein ID WP_011259680.1
Coordinates 3327542..3328465 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag EBA22_RS16435 Protein ID WP_011409027.1
Coordinates 3328462..3329061 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBA22_RS16400 3323735..3324267 + 533 Protein_2951 methyltransferase domain-containing protein -
EBA22_RS16405 3324284..3324772 - 489 WP_011409022.1 hypothetical protein -
EBA22_RS16410 3324867..3325832 + 966 Protein_2953 IS1595 family transposase -
EBA22_RS16415 3326284..3326526 - 243 WP_011409025.1 hypothetical protein -
EBA22_RS16420 3326959..3327180 + 222 Protein_2955 hypothetical protein -
EBA22_RS16425 3327253..3327462 + 210 WP_042465653.1 hypothetical protein -
EBA22_RS16430 3327542..3328465 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
EBA22_RS16435 3328462..3329061 - 600 WP_011409027.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
EBA22_RS16445 3329396..3329716 + 321 WP_011409028.1 hypothetical protein -
EBA22_RS16450 3329763..3330218 + 456 Protein_2960 BrxE family protein -
EBA22_RS16455 3330305..3331336 - 1032 WP_042465093.1 IS630 family transposase -
EBA22_RS16460 3331386..3332125 + 740 Protein_2962 DUF1819 family protein -
EBA22_RS16465 3332106..3332324 + 219 Protein_2963 DUF1788 domain-containing protein -
EBA22_RS16475 3332843..3333379 + 537 WP_011409032.1 lipocalin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T113362 WP_011259680.1 NZ_CP033191:c3328465-3327542 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T113362 NZ_CP033191:c3328465-3327542 [Xanthomonas oryzae pv. oryzae]
ATGAACGAACCTGACAAGAGCAGGCGCACTGTTGCCGCGTCGGTTCGCGCCCGGCTGCTCAACAAGGCCCGCGCCGAAAG
ACTCGACTTCAACCTGCTGCTGACCCGCTACGCGCTGGAGCGCGTCCTTTACCGCCTGAGCGTTTCGGAGCAGCAGGGTC
AATTCTTGCTCAAAGGTGCGCTGCTGTTCGACATCTGGTTCGACATACCGCATCGCCCGACGCACGATGCCGACCTGCTG
GGCTTCGGCTCCACCGAGATCCCACATCTGGAAGACCTGTTCCGCAGAATCAGTCAAATCGCCAGCGATGACGGCATCGT
GTTTCAGGCCGACAGCGTGAAGGCCGCCGAAATCCGCAAGGAGGCCAACTACGCGGGCGTCCGTGTGACGATGATCGGCC
TGCTCGATGGCGCGCGCTGCACGGTGCAGATCGACATCGGTTTCGGCGACGCCGTGACGCCCGGCCCGGACAACGTGCAG
TACCCAGTCATCCTCGACGGCATGCCGCAGCCGCAACTGCGGGTCTATCCCCGCTACACCGTGGTCGCCGAAAAGCTGGA
AGCGATGGTCAAGCTCGGCATCCTCAACAGCCGGATGAAGGACTACTTCGACCTCTGGGTTCTCGCCGGACATTCCGACT
TCGACGGTGCGGTGCTGGCCACGGCCATTCGCGCCACGTTCGAGTGCAGGGGTACGGCCATCCCACCCGGCGCGCCGCTG
GGCCTCACCGATGAGTTCGGCCTGGACGAGCAGAAGACAAAGCAGTGGCAGGCGTTCCTGCGCAAGAACACCTTGGAGCC
GATGCCGCTGACCACGGTGATCGAAGCGCTGCGCGAATTCGTGCTGCCCGTGCTGGCCGCGCTCGCGGCAGGCGAAGGTT
TCGACCGCCAGTGGCGCGCGGGCGCGGGATGGGATGCGGCCTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT113362 WP_011409027.1 NZ_CP033191:c3329061-3328462 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT113362 NZ_CP033191:c3329061-3328462 [Xanthomonas oryzae pv. oryzae]
ATGGACACGACCGTCGACAAGCTGCTGGAGCTGGTGCGCACGCGGGGACTTCTGCGCCCGCACGATCTGGCCCCACTGGG
CATCCCACGGGTGGCCCTGACGCGGGCCGTTCGGCGCGGGCAACTGGAGCGCGTCGGGCGCGGCCTGTACGGCCTGGTGG
CGCGTCCGGTGTCGGCCCACGGCACGCTGGCCGAAGTCGCGCGCCGCGTGCCCAAGGGCGTGGTCTGCCTGCTGTCGGCG
CTGCGCGTCCACGACCTGACGACCCAGGCCCCGTTCGAGGTGTGGCTGGCCATCGACAACAAGGCCGCTGCCCCGAAGCT
GGACTACCCGCCGCTACGTCTCGTGCGCTTCTCCGGGCCGGCGCTGAGCGAGGGCGTCGAGGAACACGTTGTTGATGGTG
TGCCCGTCCACGTGACCAGCGTCGCCAAGACCGTGGCCGACTGCTTCAAGTACCGCAACAAGATCGGCATCGACGTGGCG
CTGGAAGCGCTGCGCGAGGCGTGGGTTGCCCGGCGCATGACCAGCGACGAGATCTGGCACTACGCCAAGATCGACCGCGT
CGCCAACGTGATGCGTCCCTATCTGGAGAGCCTGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References