Detailed information of TA system TA113361

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2828532..2829088
• Replicon: chromosome
• Accession: NZ_CP033191
• Organism: Xanthomonas oryzae pv. oryzae strain PXO364

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: EBA22_RS14075
• Protein ID: WP_027703932.1
• Coordinates: 2828532..2828822 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: EBA22_RS14080
• Protein ID: WP_011408759.1
• Coordinates: 2828810..2829088 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EBA22_RS14025	2824302..2825393	+	1092	WP_041182166.1	ribonuclease D	-
EBA22_RS14030	2825469..2825806	-	338	Protein_2519	ATP-dependent DNA ligase	-
EBA22_RS24590	2825866..2826072	-	207	Protein_2520	hypothetical protein	-
EBA22_RS14040	2826088..2826264	-	177	Protein_2521	DUF3606 domain-containing protein	-
EBA22_RS14045	2826486..2826887	+	402	WP_011259345.1	H-NS histone family protein	-
EBA22_RS24805	2827318..2827479	-	162	WP_200898177.1	hypothetical protein	-
EBA22_RS14065	2827751..2827930	-	180	WP_015463309.1	hypothetical protein	-
EBA22_RS24595	2828074..2828271	-	198	WP_004541336.1	hypothetical protein	-
EBA22_RS14075	2828532..2828822	-	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EBA22_RS14080	2828810..2829088	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
EBA22_RS24810	2829169..2829372	-	204	WP_199285669.1	hypothetical protein	-
EBA22_RS24815	2829284..2829628	-	345	WP_199285675.1	hypothetical protein	-
EBA22_RS14090	2829573..2829773	-	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
EBA22_RS14095	2830534..2831718	-	1185	WP_011408760.1	IS256 family transposase	-
EBA22_RS14105	2832299..2833264	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
EBA22_RS14110	2833366..2833971	+	606	Protein_2533	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T113361 WP_027703932.1 NZ_CP033191:c2828822-2828532 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T113361 NZ_CP033191:c2828822-2828532 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT113361 WP_011408759.1 NZ_CP033191:c2829088-2828810 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT113361 NZ_CP033191:c2829088-2828810 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2