Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 430359..430709 Replicon chromosome
Accession NZ_CP033189
Organism Xanthomonas oryzae pv. oryzae strain PXO421

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag EBA24_RS02170 Protein ID WP_011257368.1
Coordinates 430575..430709 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag EBA24_RS02165 Protein ID WP_011407410.1
Coordinates 430359..430511 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBA24_RS02135 426630..427313 - 684 WP_011257363.1 dTMP kinase -
EBA24_RS02145 427793..428089 - 297 WP_012446308.1 hypothetical protein -
EBA24_RS02150 428096..428335 - 240 WP_011257365.1 hypothetical protein -
EBA24_RS02155 428332..429006 - 675 WP_011257366.1 hypothetical protein -
EBA24_RS02160 429328..430251 + 924 WP_011407409.1 arginase -
EBA24_RS02165 430359..430511 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
EBA24_RS02170 430575..430709 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
EBA24_RS02175 430953..431162 + 210 WP_011407411.1 CsbD family protein -
EBA24_RS02180 431331..432620 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
EBA24_RS02185 432673..433695 + 1023 WP_075240574.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T113352 WP_011257368.1 NZ_CP033189:430575-430709 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T113352 NZ_CP033189:430575-430709 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT113352 WP_011407410.1 NZ_CP033189:430359-430511 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT113352 NZ_CP033189:430359-430511 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References