Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 430374..430724 Replicon chromosome
Accession NZ_CP033188
Organism Xanthomonas oryzae pv. oryzae strain PXO513

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag EBA25_RS02175 Protein ID WP_011257368.1
Coordinates 430590..430724 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag EBA25_RS02170 Protein ID WP_011407410.1
Coordinates 430374..430526 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBA25_RS02140 426645..427328 - 684 WP_011257363.1 dTMP kinase -
EBA25_RS02150 427808..428104 - 297 WP_012446308.1 hypothetical protein -
EBA25_RS02155 428111..428350 - 240 WP_011257365.1 hypothetical protein -
EBA25_RS02160 428347..429021 - 675 WP_011257366.1 hypothetical protein -
EBA25_RS02165 429343..430266 + 924 WP_011407409.1 arginase -
EBA25_RS02170 430374..430526 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
EBA25_RS02175 430590..430724 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
EBA25_RS02180 430968..431177 + 210 WP_011407411.1 CsbD family protein -
EBA25_RS02185 431346..432635 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
EBA25_RS02190 432688..433710 + 1023 WP_075240574.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T113348 WP_011257368.1 NZ_CP033188:430590-430724 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T113348 NZ_CP033188:430590-430724 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT113348 WP_011407410.1 NZ_CP033188:430374-430526 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT113348 NZ_CP033188:430374-430526 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References