Detailed information of TA system TA113341

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/PRK09907-MazE
• Location: 2951084..2951661
• Replicon: chromosome
• Accession: NZ_CP033185
• Organism: Xanthomonas oryzae pv. oryzae strain CFBP1948

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: EBA00_RS13705
• Protein ID: WP_196381723.1
• Coordinates: 2951084..2951380 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: A0A411Y3T7
• Locus tag: EBA00_RS13710
• Protein ID: WP_017154976.1
• Coordinates: 2951419..2951661 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EBA00_RS13695	2950281..2950282	-	2	WP_107490965.1	IS3 family transposase	-
EBA00_RS13700	2950597..2950962	-	366	Protein_2462	transposase	-
EBA00_RS13705	2951084..2951380	-	297	WP_196381723.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
EBA00_RS13710	2951419..2951661	-	243	WP_017154976.1	hypothetical protein	Antitoxin
EBA00_RS13715	2951757..2953247	-	1491	WP_033003336.1	site-specific integrase	-
EBA00_RS13725	2953799..2954815	-	1017	WP_024743446.1	LysR family transcriptional regulator	-
EBA00_RS13730	2954915..2955499	+	585	WP_024743447.1	NAD(P)H-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (6-95)

Antitoxin

• Antitoxin PemI-like (4-76)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 10706.15 Da
• Isoelectric Point: 8.0458

>T113341 WP_196381723.1 NZ_CP033185:c2951380-2951084 [Xanthomonas oryzae pv. oryzae]
MDDVGGAGHEQRGDRPHLVLSSQGYNDTTSLVVCVPVTTKPKGNPFEVSLNDLNKPSVALTNQVMTADWRSRNAFPRGFA
NKAEMLQVEAKVRALLQL

Nucleotide

• Length: 297 bp

>T113341 NZ_CP033185:c2951380-2951084 [Xanthomonas oryzae pv. oryzae]
TTGGATGATGTGGGTGGGGCCGGTCATGAGCAGCGTGGGGACCGGCCACACTTGGTTCTCAGTTCGCAAGGCTACAACGA
CACAACTAGTCTAGTGGTTTGCGTTCCTGTCACAACTAAACCCAAAGGCAATCCTTTTGAAGTAAGCCTTAATGATTTGA
ACAAGCCAAGTGTTGCTTTAACAAATCAGGTCATGACGGCAGATTGGCGCAGTAGAAATGCTTTTCCCCGAGGGTTTGCT
AATAAAGCTGAAATGCTCCAAGTTGAAGCCAAGGTTCGCGCTTTGCTTCAACTTTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8786.89 Da
• Isoelectric Point: 4.3753

>AT113341 WP_017154976.1 NZ_CP033185:c2951661-2951419 [Xanthomonas oryzae pv. oryzae]
MAVLKMWGNSAAVRIPATYLEESKFSIDEPLVITAEEGRIVIESSKPSYNLADLVAQITPENTHGFAGHSQRVGAEDIEW

Nucleotide

• Length: 243 bp

>AT113341 NZ_CP033185:c2951661-2951419 [Xanthomonas oryzae pv. oryzae]
ATGGCTGTTTTGAAGATGTGGGGGAATAGTGCTGCAGTTCGAATCCCGGCGACCTATCTCGAGGAGTCCAAGTTTTCTAT
TGACGAGCCTCTTGTAATCACTGCGGAGGAAGGTCGCATTGTGATCGAGTCGAGTAAGCCGTCTTATAACCTCGCGGACT
TGGTTGCTCAAATCACTCCAGAAAACACGCACGGCTTTGCTGGGCATTCCCAGAGAGTCGGGGCGGAGGATATTGAATGG
TAA

Structures

Antitoxin

• AlphaFold DB: A0A411Y3T7