Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4257354..4257715 Replicon chromosome
Accession NZ_CP033184
Organism Xanthomonas oryzae pv. oryzae strain CFBP1949

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag EBA01_RS20410 Protein ID WP_011257368.1
Coordinates 4257354..4257488 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag EBA01_RS20415 Protein ID WP_011407410.1
Coordinates 4257563..4257715 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBA01_RS20395 4254371..4255393 - 1023 WP_165403720.1 MBL fold metallo-hydrolase -
EBA01_RS20400 4255446..4256735 - 1290 WP_024744479.1 tryptophan--tRNA ligase -
EBA01_RS20405 4256904..4257113 - 210 WP_024744478.1 CsbD family protein -
EBA01_RS20410 4257354..4257488 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
EBA01_RS20415 4257563..4257715 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
EBA01_RS20420 4257823..4258746 - 924 WP_053512953.1 arginase -
EBA01_RS20425 4259068..4259733 + 666 WP_024744476.1 hypothetical protein -
EBA01_RS20430 4259730..4260272 + 543 WP_024744475.1 GTPase -
EBA01_RS20440 4260776..4261459 + 684 WP_024744474.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T113339 WP_011257368.1 NZ_CP033184:c4257488-4257354 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T113339 NZ_CP033184:c4257488-4257354 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT113339 WP_011407410.1 NZ_CP033184:c4257715-4257563 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT113339 NZ_CP033184:c4257715-4257563 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References