113333

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4286551..4286912 Replicon chromosome
Accession NZ_CP033181
Organism Xanthomonas oryzae pv. oryzae strain CFBP7319

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag EBA04_RS20715 Protein ID WP_011257368.1
Coordinates 4286551..4286685 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag EBA04_RS20720 Protein ID WP_011407410.1
Coordinates 4286760..4286912 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBA04_RS20700 4283568..4284590 - 1023 WP_165403720.1 MBL fold metallo-hydrolase -
EBA04_RS20705 4284643..4285932 - 1290 WP_024744479.1 tryptophan--tRNA ligase -
EBA04_RS20710 4286101..4286310 - 210 WP_024744478.1 CsbD family protein -
EBA04_RS20715 4286551..4286685 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
EBA04_RS20720 4286760..4286912 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
EBA04_RS20725 4287020..4287943 - 924 WP_053512953.1 arginase -
EBA04_RS20730 4288265..4288930 + 666 WP_024744476.1 hypothetical protein -
EBA04_RS20735 4288927..4289469 + 543 WP_024744475.1 GTPase -
EBA04_RS20745 4289985..4290668 + 684 WP_024744474.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T113333 WP_011257368.1 NZ_CP033181:c4286685-4286551 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T113333 NZ_CP033181:c4286685-4286551 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT113333 WP_011407410.1 NZ_CP033181:c4286912-4286760 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT113333 NZ_CP033181:c4286912-4286760 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References