113329

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4245732..4246093 Replicon chromosome
Accession NZ_CP033179
Organism Xanthomonas oryzae pv. oryzae strain CFBP7322

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag EBA07_RS20415 Protein ID WP_011257368.1
Coordinates 4245732..4245866 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag EBA07_RS20420 Protein ID WP_011407410.1
Coordinates 4245941..4246093 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBA07_RS20400 4242749..4243771 - 1023 WP_165403720.1 MBL fold metallo-hydrolase -
EBA07_RS20405 4243824..4245113 - 1290 WP_024744479.1 tryptophan--tRNA ligase -
EBA07_RS20410 4245282..4245491 - 210 WP_024744478.1 CsbD family protein -
EBA07_RS20415 4245732..4245866 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
EBA07_RS20420 4245941..4246093 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
EBA07_RS20425 4246201..4247124 - 924 WP_053512953.1 arginase -
EBA07_RS20430 4247446..4248111 + 666 WP_024744476.1 hypothetical protein -
EBA07_RS20435 4248108..4248650 + 543 WP_024744475.1 GTPase -
EBA07_RS20445 4249178..4249861 + 684 WP_024744474.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T113329 WP_011257368.1 NZ_CP033179:c4245866-4245732 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T113329 NZ_CP033179:c4245866-4245732 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT113329 WP_011407410.1 NZ_CP033179:c4246093-4245941 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT113329 NZ_CP033179:c4246093-4245941 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References