113323

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4254590..4254951 Replicon chromosome
Accession NZ_CP033176
Organism Xanthomonas oryzae pv. oryzae strain CFBP7325

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag EBA10_RS20405 Protein ID WP_011257368.1
Coordinates 4254590..4254724 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag EBA10_RS20410 Protein ID WP_011407410.1
Coordinates 4254799..4254951 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBA10_RS20390 4251607..4252629 - 1023 WP_165403720.1 MBL fold metallo-hydrolase -
EBA10_RS20395 4252682..4253971 - 1290 WP_024744479.1 tryptophan--tRNA ligase -
EBA10_RS20400 4254140..4254349 - 210 WP_024744478.1 CsbD family protein -
EBA10_RS20405 4254590..4254724 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
EBA10_RS20410 4254799..4254951 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
EBA10_RS20415 4255059..4255982 - 924 WP_053512953.1 arginase -
EBA10_RS20420 4256304..4256969 + 666 WP_024744476.1 hypothetical protein -
EBA10_RS20425 4256966..4257508 + 543 WP_024744475.1 GTPase -
EBA10_RS20435 4258012..4258695 + 684 WP_024744474.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T113323 WP_011257368.1 NZ_CP033176:c4254724-4254590 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T113323 NZ_CP033176:c4254724-4254590 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT113323 WP_011407410.1 NZ_CP033176:c4254951-4254799 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT113323 NZ_CP033176:c4254951-4254799 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References