Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4193454..4193815 Replicon chromosome
Accession NZ_CP033173
Organism Xanthomonas oryzae pv. oryzae strain CFBP8172

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag EBA13_RS20070 Protein ID WP_011257368.1
Coordinates 4193454..4193588 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag EBA13_RS20075 Protein ID WP_011407410.1
Coordinates 4193663..4193815 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBA13_RS20055 4190471..4191493 - 1023 WP_165403720.1 MBL fold metallo-hydrolase -
EBA13_RS20060 4191546..4192835 - 1290 WP_024744479.1 tryptophan--tRNA ligase -
EBA13_RS20065 4193004..4193213 - 210 WP_024744478.1 CsbD family protein -
EBA13_RS20070 4193454..4193588 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
EBA13_RS20075 4193663..4193815 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
EBA13_RS20080 4193923..4194846 - 924 WP_053512953.1 arginase -
EBA13_RS20085 4195168..4195833 + 666 WP_024744476.1 hypothetical protein -
EBA13_RS20090 4195830..4196372 + 543 WP_024744475.1 GTPase -
EBA13_RS20100 4196876..4197559 + 684 WP_024744474.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T113317 WP_011257368.1 NZ_CP033173:c4193588-4193454 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T113317 NZ_CP033173:c4193588-4193454 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT113317 WP_011407410.1 NZ_CP033173:c4193815-4193663 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT113317 NZ_CP033173:c4193815-4193663 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References