Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 1759969..1760546 Replicon chromosome
Accession NZ_CP033172
Organism Xanthomonas oryzae pv. oryzae strain Dak16

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag EBA14_RS08930 Protein ID WP_196381723.1
Coordinates 1760250..1760546 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID A0A411Y3T7
Locus tag EBA14_RS08925 Protein ID WP_017154976.1
Coordinates 1759969..1760211 (+) Length 81 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBA14_RS08905 1756131..1756715 - 585 WP_024743447.1 NAD(P)H-dependent oxidoreductase -
EBA14_RS08910 1756815..1757831 + 1017 WP_024743446.1 LysR family transcriptional regulator -
EBA14_RS08920 1758383..1759873 + 1491 WP_033003336.1 site-specific integrase -
EBA14_RS08925 1759969..1760211 + 243 WP_017154976.1 hypothetical protein Antitoxin
EBA14_RS08930 1760250..1760546 + 297 WP_196381723.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
EBA14_RS08935 1760668..1761033 + 366 Protein_1613 transposase -
EBA14_RS08940 1761099..1762200 + 1102 WP_107490965.1 IS3 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-95)

Antitoxin

(4-76)


Sequences


Toxin        


Download         Length: 99 a.a.        Molecular weight: 10706.15 Da        Isoelectric Point: 8.0458

>T113314 WP_196381723.1 NZ_CP033172:1760250-1760546 [Xanthomonas oryzae pv. oryzae]
MDDVGGAGHEQRGDRPHLVLSSQGYNDTTSLVVCVPVTTKPKGNPFEVSLNDLNKPSVALTNQVMTADWRSRNAFPRGFA
NKAEMLQVEAKVRALLQL

Download         Length: 297 bp

>T113314 NZ_CP033172:1760250-1760546 [Xanthomonas oryzae pv. oryzae]
TTGGATGATGTGGGTGGGGCCGGTCATGAGCAGCGTGGGGACCGGCCACACTTGGTTCTCAGTTCGCAAGGCTACAACGA
CACAACTAGTCTAGTGGTTTGCGTTCCTGTCACAACTAAACCCAAAGGCAATCCTTTTGAAGTAAGCCTTAATGATTTGA
ACAAGCCAAGTGTTGCTTTAACAAATCAGGTCATGACGGCAGATTGGCGCAGTAGAAATGCTTTTCCCCGAGGGTTTGCT
AATAAAGCTGAAATGCTCCAAGTTGAAGCCAAGGTTCGCGCTTTGCTTCAACTTTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8786.89 Da        Isoelectric Point: 4.3753

>AT113314 WP_017154976.1 NZ_CP033172:1759969-1760211 [Xanthomonas oryzae pv. oryzae]
MAVLKMWGNSAAVRIPATYLEESKFSIDEPLVITAEEGRIVIESSKPSYNLADLVAQITPENTHGFAGHSQRVGAEDIEW

Download         Length: 243 bp

>AT113314 NZ_CP033172:1759969-1760211 [Xanthomonas oryzae pv. oryzae]
ATGGCTGTTTTGAAGATGTGGGGGAATAGTGCTGCAGTTCGAATCCCGGCGACCTATCTCGAGGAGTCCAAGTTTTCTAT
TGACGAGCCTCTTGTAATCACTGCGGAGGAAGGTCGCATTGTGATCGAGTCGAGTAAGCCGTCTTATAACCTCGCGGACT
TGGTTGCTCAAATCACTCCAGAAAACACGCACGGCTTTGCTGGGCATTCCCAGAGAGTCGGGGCGGAGGATATTGAATGG
TAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A411Y3T7

References