Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 271877..272457 Replicon chromosome
Accession NZ_CP033162
Organism Serratia sp. P2ACOL2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EBA31_RS01375 Protein ID WP_122076795.1
Coordinates 272173..272457 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EBA31_RS01370 Protein ID WP_122076792.1
Coordinates 271877..272164 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBA31_RS01345 267615..268700 - 1086 WP_048762826.1 carbon-phosphorus lyase complex subunit PhnI -
EBA31_RS01350 268700..269281 - 582 WP_122076786.1 phosphonate C-P lyase system protein PhnH -
EBA31_RS01355 269284..269727 - 444 WP_046374634.1 phosphonate C-P lyase system protein PhnG -
EBA31_RS01360 269728..270453 - 726 WP_170868571.1 phosphonate metabolism transcriptional regulator PhnF -
EBA31_RS01365 270714..271772 + 1059 WP_122076789.1 permease -
EBA31_RS01370 271877..272164 + 288 WP_122076792.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EBA31_RS01375 272173..272457 + 285 WP_122076795.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EBA31_RS01380 272454..272918 - 465 WP_046374631.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
EBA31_RS01385 273092..275230 - 2139 WP_020824988.1 anaerobic ribonucleoside-triphosphate reductase -
EBA31_RS01390 275514..276422 - 909 WP_020824989.1 LysR family transcriptional regulator -
EBA31_RS01395 276527..277051 + 525 WP_048762834.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-44)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11083.75 Da        Isoelectric Point: 4.7160

>T113290 WP_122076795.1 NZ_CP033162:272173-272457 [Serratia sp. P2ACOL2]
MRVEWDEEALRDRERIFDFLYPFNPQAAEQADAEIDKAVKRLLDYPELGKIWYRQARKLLVSQASLLVLYVVVDDVIKVL
AVAHQREKLPDIEN

Download         Length: 285 bp

>T113290 NZ_CP033162:272173-272457 [Serratia sp. P2ACOL2]
ATGCGTGTCGAATGGGATGAAGAAGCGCTACGGGACAGGGAACGTATTTTTGATTTTCTCTATCCTTTTAATCCACAGGC
TGCTGAGCAGGCTGATGCTGAGATTGATAAGGCAGTGAAGCGCCTGTTGGATTACCCTGAACTCGGTAAAATTTGGTACA
GACAGGCGCGTAAGTTATTGGTCAGCCAGGCTTCGTTATTAGTTTTATACGTTGTTGTCGACGACGTGATTAAGGTTTTA
GCCGTTGCTCATCAACGAGAGAAACTCCCCGACATAGAGAACTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11070.42 Da        Isoelectric Point: 6.4766

>AT113290 WP_122076792.1 NZ_CP033162:271877-272164 [Serratia sp. P2ACOL2]
MESRIQFRIEDETKRLAQKAAEAKGITLSEACRRLAEQMADEQRATEQHENWLKEKVDAAFARLHEGSAVYLDQQQVDEN
MDAFKAKVRAKYDRK

Download         Length: 288 bp

>AT113290 NZ_CP033162:271877-272164 [Serratia sp. P2ACOL2]
ATGGAAAGCCGTATCCAGTTTCGCATTGAGGATGAGACTAAACGTTTGGCGCAGAAAGCCGCAGAAGCCAAGGGGATCAC
TTTGAGTGAGGCGTGTCGACGTTTGGCTGAGCAAATGGCGGATGAGCAACGGGCCACTGAGCAACATGAAAATTGGTTGA
AAGAAAAGGTTGATGCCGCTTTTGCCCGTTTGCATGAAGGAAGTGCGGTCTATCTTGACCAGCAACAGGTTGATGAAAAC
ATGGATGCCTTTAAGGCAAAAGTCCGAGCGAAATACGACCGAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References