Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1059168..1059727 Replicon chromosome
Accession NZ_CP033144
Organism Vibrio owensii strain V180403

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D0856_RS05400 Protein ID WP_122067420.1
Coordinates 1059168..1059446 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A347UR21
Locus tag D0856_RS05405 Protein ID WP_005398409.1
Coordinates 1059443..1059727 (-) Length 95 a.a.

Genomic Context

D0856_RS05330D0856_RS30765D0856_RS05340D0856_RS05345D0856_RS05350D0856_RS30770D0856_RS30535D0856_RS05365D0856_RS05370D0856_RS05375D0856_RS05380D0856_RS05390D0856_RS05410D0856_RS05415D0856_RS05420D0856_RS05425D0856_RS05435D0856_RS05440D0856_RS05445D0856_RS05450D0856_RS05455D0856_RS05460D0856_RS05400D0856_RS05405
Location: 1054468..1054557 (90 bp)
Type: Others
Protein ID: WP_072039143.1
Location: 1054998..1055087 (90 bp)
Type: Others
Protein ID: WP_206387585.1
Location: 1055161..1055649 (489 bp)
Type: Others
Protein ID: WP_122068875.1
Location: 1055675..1055767 (93 bp)
Type: Others
Protein ID: Protein_1015
Location: 1055802..1056074 (273 bp)
Type: Others
Protein ID: WP_122067413.1
Location: 1056166..1056258 (93 bp)
Type: Others
Protein ID: WP_206387564.1
Location: 1056485..1056652 (168 bp)
Type: Others
Protein ID: WP_163000551.1
Location: 1056823..1057293 (471 bp)
Type: Others
Protein ID: WP_122067416.1
Location: 1057323..1057415 (93 bp)
Type: Others
Protein ID: WP_206387565.1
Location: 1057452..1057829 (378 bp)
Type: Others
Protein ID: WP_122067418.1
Location: 1057844..1057936 (93 bp)
Type: Others
Protein ID: WP_206387566.1
Location: 1058361..1059005 (645 bp)
Type: Others
Protein ID: WP_017191304.1
Location: 1059991..1060299 (309 bp)
Type: Others
Protein ID: WP_122067421.1
Location: 1060337..1060426 (90 bp)
Type: Others
Protein ID: WP_071881309.1
Location: 1060495..1060851 (357 bp)
Type: Others
Protein ID: WP_020198239.1
Location: 1060885..1060976 (92 bp)
Type: Others
Protein ID: Protein_1029
Location: 1061437..1061526 (90 bp)
Type: Others
Protein ID: WP_122068877.1
Location: 1061639..1062529 (891 bp)
Type: Others
Protein ID: WP_163000572.1
Location: 1062529..1063077 (549 bp)
Type: Others
Protein ID: WP_122067424.1
Location: 1063102..1063194 (93 bp)
Type: Others
Protein ID: WP_122067425.1
Location: 1063237..1063983 (747 bp)
Type: Others
Protein ID: WP_122067426.1
Location: 1064005..1064097 (93 bp)
Type: Others
Protein ID: WP_079752431.1
Location: 1059168..1059446 (279 bp)
Type: Toxin
Protein ID: WP_122067420.1
Location: 1059443..1059727 (285 bp)
Type: Antitoxin
Protein ID: WP_005398409.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D0856_RS053301054468..1054557+90WP_072039143.1DUF3265 domain-containing protein-
D0856_RS307651054998..1055087+90WP_206387585.1DUF3265 domain-containing protein-
D0856_RS053401055161..1055649+489WP_122068875.1hypothetical protein-
D0856_RS053451055675..1055767+93Protein_1015DUF3265 domain-containing protein-
D0856_RS053501055802..1056074+273WP_122067413.1hypothetical protein-
D0856_RS307701056166..1056258+93WP_206387564.1DUF3265 domain-containing protein-
D0856_RS305351056485..1056652+168WP_163000551.1hypothetical protein-
D0856_RS053651056823..1057293+471WP_122067416.1GNAT family N-acetyltransferase-
D0856_RS053701057323..1057415+93WP_206387565.1DUF3265 domain-containing protein-
D0856_RS053751057452..1057829+378WP_122067418.1hypothetical protein-
D0856_RS053801057844..1057936+93WP_206387566.1DUF3265 domain-containing protein-
D0856_RS053901058361..1059005+645WP_017191304.1hypothetical protein-
D0856_RS054001059168..1059446-279WP_122067420.1type II toxin-antitoxin system RelE/ParE family toxinToxin
D0856_RS054051059443..1059727-285WP_005398409.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
D0856_RS054101059991..1060299+309WP_122067421.1hypothetical protein-
D0856_RS054151060337..1060426+90WP_071881309.1DUF3265 domain-containing protein-
D0856_RS054201060495..1060851+357WP_020198239.1hypothetical protein-
D0856_RS054251060885..1060976+92Protein_1029DUF3265 domain-containing protein-
D0856_RS054351061437..1061526+90WP_122068877.1DUF3265 domain-containing protein-
D0856_RS054401061639..1062529+891WP_163000572.1DUF4747 family protein-
D0856_RS054451062529..1063077+549WP_122067424.1hypothetical protein-
D0856_RS054501063102..1063194+93WP_122067425.1DUF3265 domain-containing protein-
D0856_RS054551063237..1063983+747WP_122067426.1hypothetical protein-
D0856_RS054601064005..1064097+93WP_079752431.1DUF3265 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--1003789..109908795298
-insideIntegron--1002589..109025787668


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-69)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10832.55 Da        Isoelectric Point: 4.5332

>T113251 WP_122067420.1 NZ_CP033144:c1059446-1059168 [Vibrio owensii]
MILWEEESLNDREKIFEFLYGFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGNIIRVM
RVLHQKQKFPTD

Download         Length: 279 bp

>T113251 NZ_CP033144:c1059446-1059168 [Vibrio owensii]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGGCTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGTGTACAACGAGATGGCA
TCCGCGGACGATTACTCATTATTCCTGAGATTTCGATGATTGTCTCTTACTGGGTCGAGGGCAATATTATCCGAGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACGGATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11069.40 Da        Isoelectric Point: 9.2167

>AT113251 WP_005398409.1 NZ_CP033144:c1059727-1059443 [Vibrio owensii]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp

>AT113251 NZ_CP033144:c1059727-1059443 [Vibrio owensii]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGCAC
TCTAAGTGACGCATGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTGTCTCACGATGCATGGTTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCCGTTTTCGTTGAGCACCAAACTGCTAAATCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A347UR21

References