Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1049239..1049798 Replicon chromosome
Accession NZ_CP033144
Organism Vibrio owensii strain V180403

Toxin (Protein)


Gene name relE Uniprot ID A0A347UR22
Locus tag D0856_RS05265 Protein ID WP_005398411.1
Coordinates 1049239..1049517 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A347UR21
Locus tag D0856_RS05270 Protein ID WP_005398409.1
Coordinates 1049514..1049798 (-) Length 95 a.a.

Genomic Context

D0856_RS05200D0856_RS05210D0856_RS30530D0856_RS05220D0856_RS05225D0856_RS05230D0856_RS05235D0856_RS05240D0856_RS05245D0856_RS05260D0856_RS05275D0856_RS05285D0856_RS05290D0856_RS05295D0856_RS05300D0856_RS05305D0856_RS05310D0856_RS05320D0856_RS05325D0856_RS05330D0856_RS05250D0856_RS05255D0856_RS05265D0856_RS05270D0856_RS05280
Location: 1044311..1045144 (834 bp)
Type: Others
Protein ID: WP_122067396.1
Location: 1045276..1045971 (696 bp)
Type: Others
Protein ID: WP_122067397.1
Location: 1046310..1046459 (150 bp)
Type: Others
Protein ID: WP_163000571.1
Location: 1046628..1047188 (561 bp)
Type: Others
Protein ID: WP_049877106.1
Location: 1047203..1047295 (93 bp)
Type: Others
Protein ID: WP_198039109.1
Location: 1047331..1047708 (378 bp)
Type: Others
Protein ID: WP_122067398.1
Location: 1047693..1047815 (123 bp)
Type: Others
Protein ID: WP_082314566.1
Location: 1047909..1048265 (357 bp)
Type: Others
Protein ID: WP_122067399.1
Location: 1048366..1048455 (90 bp)
Type: Others
Protein ID: WP_071881309.1
Location: 1049119..1049210 (92 bp)
Type: Others
Protein ID: Protein_999
Location: 1049875..1049988 (114 bp)
Type: Others
Protein ID: WP_122067402.1
Location: 1050649..1050741 (93 bp)
Type: Others
Protein ID: WP_122067403.1
Location: 1050769..1051068 (300 bp)
Type: Others
Protein ID: WP_122067404.1
Location: 1051065..1051187 (123 bp)
Type: Others
Protein ID: WP_122067405.1
Location: 1051250..1051762 (513 bp)
Type: Others
Protein ID: WP_122067406.1
Location: 1051781..1051873 (93 bp)
Type: Others
Protein ID: WP_122067407.1
Location: 1051924..1053372 (1449 bp)
Type: Others
Protein ID: WP_206387563.1
Location: 1053928..1054017 (90 bp)
Type: Others
Protein ID: WP_123768104.1
Location: 1054050..1054445 (396 bp)
Type: Others
Protein ID: WP_122067411.1
Location: 1054468..1054557 (90 bp)
Type: Others
Protein ID: WP_072039143.1
Location: 1048484..1048753 (270 bp)
Type: Others
Protein ID: WP_122067401.1
Location: 1048758..1049042 (285 bp)
Type: Others
Protein ID: WP_005398409.1
Location: 1049239..1049517 (279 bp)
Type: Toxin
Protein ID: WP_005398411.1
Location: 1049514..1049798 (285 bp)
Type: Antitoxin
Protein ID: WP_005398409.1
Location: 1050032..1050526 (495 bp)
Type: Others
Protein ID: WP_023623381.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D0856_RS052001044311..1045144+834WP_122067396.1EcsC family protein-
D0856_RS052101045276..1045971+696WP_122067397.1FRG domain-containing protein-
D0856_RS305301046310..1046459+150WP_163000571.1hypothetical protein-
D0856_RS052201046628..1047188+561WP_049877106.1YdcF family protein-
D0856_RS052251047203..1047295+93WP_198039109.1DUF3265 domain-containing protein-
D0856_RS052301047331..1047708+378WP_122067398.1hypothetical protein-
D0856_RS052351047693..1047815+123WP_082314566.1DUF3265 domain-containing protein-
D0856_RS052401047909..1048265+357WP_122067399.1hypothetical protein-
D0856_RS052451048366..1048455+90WP_071881309.1DUF3265 domain-containing protein-
D0856_RS052501048484..1048753-270WP_122067401.1type II toxin-antitoxin system RelE/ParE family toxin-
D0856_RS052551048758..1049042-285WP_005398409.1type II toxin-antitoxin system RelB/DinJ family antitoxin-
D0856_RS052601049119..1049210+92Protein_999DUF3265 domain-containing protein-
D0856_RS052651049239..1049517-279WP_005398411.1type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE familyToxin
D0856_RS052701049514..1049798-285WP_005398409.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
D0856_RS052751049875..1049988+114WP_122067402.1DUF3265 domain-containing protein-
D0856_RS052801050032..1050526-495WP_023623381.1hypothetical protein-
D0856_RS052851050649..1050741+93WP_122067403.1DUF3265 domain-containing protein-
D0856_RS052901050769..1051068+300WP_122067404.1hypothetical protein-
D0856_RS052951051065..1051187+123WP_122067405.1DUF3265 domain-containing protein-
D0856_RS053001051250..1051762+513WP_122067406.1hypothetical protein-
D0856_RS053051051781..1051873+93WP_122067407.1DUF3265 domain-containing protein-
D0856_RS053101051924..1053372+1449WP_206387563.1caspase family protein-
D0856_RS053201053928..1054017+90WP_123768104.1DUF3265 domain-containing protein-
D0856_RS053251054050..1054445+396WP_122067411.1hypothetical protein-
D0856_RS053301054468..1054557+90WP_072039143.1DUF3265 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--1003789..109908795298
-insideIntegron--1002589..109025787668


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-69)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10891.57 Da        Isoelectric Point: 4.3430

>T113250 WP_005398411.1 NZ_CP033144:c1049517-1049239 [Vibrio owensii]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD

Download         Length: 279 bp

>T113250 NZ_CP033144:c1049517-1049239 [Vibrio owensii]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTGATGGGTGTACAACGAGATGGCA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTCTCTTACTGGGTCGAGGGCGATATCATCAGAGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACGGATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11069.40 Da        Isoelectric Point: 9.2167

>AT113250 WP_005398409.1 NZ_CP033144:c1049798-1049514 [Vibrio owensii]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp

>AT113250 NZ_CP033144:c1049798-1049514 [Vibrio owensii]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGAAC
TCTAAGTGATGCTTGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCTGTTTTCGTTGAGCACCAAACTGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A347UR22

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A347UR21

References