Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1015999..1016558 Replicon chromosome
Accession NZ_CP033144
Organism Vibrio owensii strain V180403

Toxin (Protein)


Gene name relE Uniprot ID A0A347UR22
Locus tag D0856_RS04825 Protein ID WP_005398411.1
Coordinates 1015999..1016277 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A347UR21
Locus tag D0856_RS04830 Protein ID WP_005398409.1
Coordinates 1016274..1016558 (-) Length 95 a.a.

Genomic Context

D0856_RS04750D0856_RS30730D0856_RS04760D0856_RS30735D0856_RS04775D0856_RS04790D0856_RS04795D0856_RS04800D0856_RS04805D0856_RS04810D0856_RS04815D0856_RS04820D0856_RS04835D0856_RS04840D0856_RS04845D0856_RS04850D0856_RS04855D0856_RS04860D0856_RS04865D0856_RS04870D0856_RS04875D0856_RS04880D0856_RS04885D0856_RS04890D0856_RS04895D0856_RS30740D0856_RS04825D0856_RS04830
Location: 1011238..1011627 (390 bp)
Type: Others
Protein ID: WP_122067354.1
Location: 1011645..1011734 (90 bp)
Type: Others
Protein ID: WP_071881309.1
Location: 1011760..1012317 (558 bp)
Type: Others
Protein ID: WP_122067355.1
Location: 1012340..1012432 (93 bp)
Type: Others
Protein ID: WP_005536857.1
Location: 1012959..1013050 (92 bp)
Type: Others
Protein ID: Protein_911
Location: 1013538..1013669 (132 bp)
Type: Others
Protein ID: WP_122067358.1
Location: 1013703..1014422 (720 bp)
Type: Others
Protein ID: WP_122067359.1
Location: 1014437..1014529 (93 bp)
Type: Others
Protein ID: WP_072884142.1
Location: 1014562..1015011 (450 bp)
Type: Others
Protein ID: WP_122067360.1
Location: 1015053..1015142 (90 bp)
Type: Others
Protein ID: WP_206387583.1
Location: 1015185..1015853 (669 bp)
Type: Others
Protein ID: WP_122067362.1
Location: 1015881..1015970 (90 bp)
Type: Others
Protein ID: WP_122068866.1
Location: 1016635..1016736 (102 bp)
Type: Others
Protein ID: Protein_921
Location: 1016773..1017591 (819 bp)
Type: Others
Protein ID: WP_122068868.1
Location: 1017611..1017703 (93 bp)
Type: Others
Protein ID: WP_122067363.1
Location: 1018158..1018250 (93 bp)
Type: Others
Protein ID: WP_017821981.1
Location: 1018298..1018885 (588 bp)
Type: Others
Protein ID: WP_038880370.1
Location: 1018900..1018992 (93 bp)
Type: Others
Protein ID: WP_079855765.1
Location: 1019037..1019453 (417 bp)
Type: Others
Protein ID: WP_163000628.1
Location: 1019479..1019571 (93 bp)
Type: Others
Protein ID: WP_206169873.1
Location: 1019598..1020008 (411 bp)
Type: Others
Protein ID: WP_031847708.1
Location: 1019998..1020132 (135 bp)
Type: Others
Protein ID: WP_122067366.1
Location: 1020219..1020779 (561 bp)
Type: Others
Protein ID: WP_058666954.1
Location: 1020795..1020926 (132 bp)
Type: Others
Protein ID: WP_206387584.1
Location: 1020923..1021432 (510 bp)
Type: Others
Protein ID: WP_122067368.1
Location: 1021455..1021547 (93 bp)
Type: Others
Protein ID: WP_086375043.1
Location: 1015999..1016277 (279 bp)
Type: Toxin
Protein ID: WP_005398411.1
Location: 1016274..1016558 (285 bp)
Type: Antitoxin
Protein ID: WP_005398409.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D0856_RS047501011238..1011627+390WP_122067354.1DUF4345 domain-containing protein-
D0856_RS307301011645..1011734+90WP_071881309.1DUF3265 domain-containing protein-
D0856_RS047601011760..1012317+558WP_122067355.1nucleotidyltransferase family protein-
D0856_RS307351012340..1012432+93WP_005536857.1DUF3265 domain-containing protein-
D0856_RS047751012959..1013050+92Protein_911DUF3265 domain-containing protein-
D0856_RS047901013538..1013669+132WP_122067358.1DUF3265 domain-containing protein-
D0856_RS047951013703..1014422+720WP_122067359.1hypothetical protein-
D0856_RS048001014437..1014529+93WP_072884142.1DUF3265 domain-containing protein-
D0856_RS048051014562..1015011+450WP_122067360.1metal ABC transporter ATPase-
D0856_RS048101015053..1015142+90WP_206387583.1DUF3265 domain-containing protein-
D0856_RS048151015185..1015853+669WP_122067362.1hypothetical protein-
D0856_RS048201015881..1015970+90WP_122068866.1DUF3265 domain-containing protein-
D0856_RS048251015999..1016277-279WP_005398411.1type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE familyToxin
D0856_RS048301016274..1016558-285WP_005398409.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
D0856_RS048351016635..1016736+102Protein_921DUF3265 domain-containing protein-
D0856_RS048401016773..1017591+819WP_122068868.1DUF2971 domain-containing protein-
D0856_RS048451017611..1017703+93WP_122067363.1DUF3265 domain-containing protein-
D0856_RS048501018158..1018250+93WP_017821981.1DUF3265 domain-containing protein-
D0856_RS048551018298..1018885+588WP_038880370.1sugar O-acetyltransferase-
D0856_RS048601018900..1018992+93WP_079855765.1DUF3265 domain-containing protein-
D0856_RS048651019037..1019453+417WP_163000628.1GNAT family N-acetyltransferase-
D0856_RS048701019479..1019571+93WP_206169873.1DUF3265 domain-containing protein-
D0856_RS048751019598..1020008+411WP_031847708.1hydrolase-
D0856_RS048801019998..1020132+135WP_122067366.1DUF3265 domain-containing protein-
D0856_RS048851020219..1020779+561WP_058666954.1hypothetical protein-
D0856_RS048901020795..1020926+132WP_206387584.1DUF3265 domain-containing protein-
D0856_RS048951020923..1021432+510WP_122067368.1DUF4303 domain-containing protein-
D0856_RS307401021455..1021547+93WP_086375043.1DUF3265 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--1003789..109908795298
-insideIntegron--1002589..109025787668


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-69)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10891.57 Da        Isoelectric Point: 4.3430

>T113248 WP_005398411.1 NZ_CP033144:c1016277-1015999 [Vibrio owensii]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD

Download         Length: 279 bp

>T113248 NZ_CP033144:c1016277-1015999 [Vibrio owensii]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAATCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGTGTACAACGAGATGGCA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTCTCTTATTGGGTCGAGGGCGATATCATCAGAGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACGGATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11069.40 Da        Isoelectric Point: 9.2167

>AT113248 WP_005398409.1 NZ_CP033144:c1016558-1016274 [Vibrio owensii]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp

>AT113248 NZ_CP033144:c1016558-1016274 [Vibrio owensii]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGCAC
TCTGAGTGACGCATGTCGTGAACTTACAGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCTGTTTTCGTTGAGCACCAAACTGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A347UR22

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A347UR21

References