Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 219171..219934 Replicon chromosome
Accession NZ_CP033144
Organism Vibrio owensii strain V180403

Toxin (Protein)


Gene name ataT Uniprot ID A0A919BFZ0
Locus tag D0856_RS01040 Protein ID WP_023584043.1
Coordinates 219171..219677 (-) Length 169 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag D0856_RS01045 Protein ID WP_000212004.1
Coordinates 219668..219934 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D0856_RS01000 214245..214523 - 279 WP_054103798.1 helix-turn-helix domain-containing protein -
D0856_RS01005 214520..214843 - 324 WP_054103799.1 type II toxin-antitoxin system RelE/ParE family toxin -
D0856_RS01010 215024..215305 + 282 WP_000433889.1 type IV conjugative transfer system protein TraL -
D0856_RS01015 215302..215928 + 627 WP_000667170.1 hypothetical protein -
D0856_RS01020 215912..216808 + 897 WP_086597854.1 type-F conjugative transfer system secretin TraK -
D0856_RS01025 216811..218100 + 1290 WP_086597841.1 TraB/VirB10 family protein -
D0856_RS01030 218175..218747 + 573 WP_001944091.1 type IV conjugative transfer system lipoprotein TraV -
D0856_RS01035 218744..219130 + 387 WP_023584042.1 hypothetical protein -
D0856_RS01040 219171..219677 - 507 WP_023584043.1 GNAT family N-acetyltransferase Toxin
D0856_RS01045 219668..219934 - 267 WP_000212004.1 DUF1778 domain-containing protein Antitoxin
D0856_RS01050 220750..223479 + 2730 WP_122067049.1 AAA family ATPase -
D0856_RS01055 223476..224585 + 1110 WP_122067050.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-146)

Antitoxin

Vibrio phage ICP1, Orf50

(8-83)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18278.00 Da        Isoelectric Point: 7.2132

>T113247 WP_023584043.1 NZ_CP033144:c219677-219171 [Vibrio owensii]
MGISAPTLLTDEHQLNAFQCGIEELDTWLRKQALKSQKRGTARVYVVNDTDAHQVVGYYAIAMGSVSREQAFSSLRRNSP
DPIPMVILARLGVDNAYQGQGIAAGLLKDCIIRSVQAMNAVGGAGILVHAIDGSAQTFYKKFGFKESTFDPLVLMARICD
IEKSLSID

Download         Length: 507 bp

>T113247 NZ_CP033144:c219677-219171 [Vibrio owensii]
TTGGGAATAAGTGCACCAACCCTCCTCACTGATGAGCACCAGCTTAATGCCTTTCAATGTGGCATTGAAGAGCTCGATAC
TTGGTTAAGAAAACAGGCGTTAAAGAGTCAAAAGCGGGGAACCGCGAGGGTGTATGTGGTCAATGACACTGACGCCCATC
AAGTGGTCGGGTACTATGCCATTGCCATGGGATCAGTTTCCAGAGAGCAAGCTTTTAGTTCATTAAGAAGAAATAGTCCA
GATCCCATTCCCATGGTGATTCTAGCCAGACTTGGAGTAGATAACGCCTATCAAGGTCAAGGCATTGCGGCAGGTCTTTT
AAAAGATTGTATCATTCGCTCAGTACAAGCAATGAACGCTGTCGGTGGAGCAGGAATCTTAGTCCATGCTATTGATGGTA
GTGCGCAAACGTTCTACAAGAAATTTGGCTTCAAAGAATCGACGTTTGATCCATTAGTACTCATGGCAAGGATCTGCGAT
ATCGAAAAATCATTGTCGATAGACTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9956.48 Da        Isoelectric Point: 5.8580

>AT113247 WP_000212004.1 NZ_CP033144:c219934-219668 [Vibrio owensii]
MATKTAPINMRVLPSVRDIIDAAASLKKVDRTVFIQQAALNEAHSILAEQRDFVLEAKAFEAFDNELRAEPQTLEGMKDL
FKRKAPWE

Download         Length: 267 bp

>AT113247 NZ_CP033144:c219934-219668 [Vibrio owensii]
ATGGCTACAAAGACAGCCCCAATCAACATGCGAGTACTGCCATCGGTAAGAGACATCATCGATGCCGCAGCAAGTTTAAA
AAAAGTTGATAGAACCGTGTTCATTCAGCAAGCAGCGCTCAATGAAGCGCATAGTATACTGGCAGAACAGCGGGATTTTG
TTCTAGAAGCAAAGGCTTTTGAAGCGTTTGATAACGAACTTCGTGCAGAGCCACAGACTCTTGAAGGTATGAAAGATCTG
TTTAAGAGGAAAGCGCCTTGGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References