Detailed information of TA system TA113245

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 55430..55958
• Replicon: plasmid pVPWZ1
• Accession: NZ_CP033143
• Organism: Vibrio parahaemolyticus strain 160807

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: D0871_RS26475
• Protein ID: WP_025788842.1
• Coordinates: 55674..55958 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: D0871_RS26470
• Protein ID: WP_025788840.1
• Coordinates: 55430..55684 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D0871_RS27015	51358..51501	-	144	WP_153189405.1	hypothetical protein	-
D0871_RS26450	51901..52287	-	387	WP_025792428.1	hypothetical protein	-
D0871_RS26455	52425..53027	-	603	WP_023623175.1	recombinase family protein	-
D0871_RS26460	53360..54469	+	1110	WP_122016162.1	hypothetical protein	-
D0871_RS26465	54472..54933	+	462	WP_122016163.1	hypothetical protein	-
D0871_RS26470	55430..55684	+	255	WP_025788840.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
D0871_RS26475	55674..55958	+	285	WP_025788842.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
D0871_RS26480	55972..56262	+	291	WP_025788843.1	hypothetical protein	-
D0871_RS26485	56275..56526	+	252	WP_025788844.1	hypothetical protein	-
D0871_RS26490	56539..56745	+	207	WP_122016164.1	hypothetical protein	-
D0871_RS26495	57002..57472	-	471	WP_122016165.1	hypothetical protein	-
D0871_RS26500	57764..58021	+	258	WP_017449219.1	hypothetical protein	-
D0871_RS26505	58236..59141	+	906	WP_071653130.1	DUF1738 domain-containing protein	-
D0871_RS26510	59211..59552	+	342	WP_122016166.1	hypothetical protein	-
D0871_RS26515	59713..60126	+	414	WP_017449216.1	antirestriction protein	-
D0871_RS26520	60232..60624	+	393	WP_024700500.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..106229	106229

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11114.13 Da
• Isoelectric Point: 10.8169

>T113245 WP_025788842.1 NZ_CP033143:55674-55958 [Vibrio parahaemolyticus]
MTYKLVFKVEAEKEWRKLDSTIRSQFKKKLIERLENPHVPTAKLSSMQNCYKIKLRSAGYRLVYQVRDQEVVISVVAVGK
RERNQVYKIAAKRV

Nucleotide

• Length: 285 bp

>T113245 NZ_CP033143:55674-55958 [Vibrio parahaemolyticus]
ATGACCTATAAGTTAGTTTTCAAGGTTGAGGCAGAGAAAGAATGGCGCAAGTTGGACAGCACCATTAGGTCTCAGTTTAA
GAAGAAGTTGATTGAACGTTTAGAAAATCCGCATGTACCAACGGCAAAGTTAAGTAGTATGCAGAACTGCTACAAAATAA
AACTGAGAAGCGCCGGATACCGTCTTGTCTATCAAGTAAGAGATCAGGAAGTGGTTATTTCAGTTGTGGCCGTTGGTAAG
CGTGAACGTAATCAAGTTTACAAAATCGCAGCAAAGCGAGTGTAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9478.80 Da
• Isoelectric Point: 3.9953

>AT113245 WP_025788840.1 NZ_CP033143:55430-55684 [Vibrio parahaemolyticus]
MTTIRPILADNSTSISELKKNPMAVIEQADGFPVAVLNRNQPAFYCVPADAYEMLMDKLEDIELAQIVKEREHSEEIEIS
IDDL

Nucleotide

• Length: 255 bp

>AT113245 NZ_CP033143:55430-55684 [Vibrio parahaemolyticus]
ATGACAACAATTCGTCCTATTCTCGCTGATAACTCAACAAGTATTAGCGAACTTAAAAAGAACCCTATGGCAGTCATAGA
ACAAGCAGACGGGTTCCCCGTTGCGGTACTGAACCGTAATCAACCAGCATTTTATTGCGTTCCTGCTGATGCCTATGAAA
TGCTCATGGATAAACTGGAAGATATTGAGCTTGCTCAAATAGTTAAAGAGCGTGAGCATTCAGAAGAAATAGAGATCAGC
ATCGATGACCTATAA