Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE-RelB |
Location | 1474256..1474815 | Replicon | chromosome |
Accession | NZ_CP033137 | ||
Organism | Vibrio owensii strain 1700302 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A347UR22 |
Locus tag | D0812_RS06930 | Protein ID | WP_005398411.1 |
Coordinates | 1474256..1474534 (-) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A3G2PT85 |
Locus tag | D0812_RS06935 | Protein ID | WP_054824926.1 |
Coordinates | 1474531..1474815 (-) | Length | 95 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
D0812_RS06905 | 1470788..1471372 | + | 585 | WP_038896808.1 | ribosomal protein S5-alanine N-acetyltransferase | - |
D0812_RS06910 | 1471373..1471960 | + | 588 | WP_054824176.1 | HD domain-containing protein | - |
D0812_RS06915 | 1471974..1472447 | + | 474 | WP_054824177.1 | DUF2947 domain-containing protein | - |
D0812_RS06920 | 1472506..1473468 | - | 963 | WP_054824178.1 | integron integrase | - |
D0812_RS06930 | 1474256..1474534 | - | 279 | WP_005398411.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
D0812_RS06935 | 1474531..1474815 | - | 285 | WP_054824926.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
D0812_RS06940 | 1474892..1475005 | + | 114 | WP_104047644.1 | DUF3265 domain-containing protein | - |
D0812_RS06945 | 1475438..1475530 | + | 93 | WP_005445221.1 | DUF3265 domain-containing protein | - |
D0812_RS06950 | 1475562..1475990 | + | 429 | WP_054824934.1 | ester cyclase | - |
D0812_RS06955 | 1476005..1476097 | + | 93 | WP_194842408.1 | DUF3265 domain-containing protein | - |
D0812_RS06960 | 1476201..1476467 | + | 267 | WP_041061928.1 | hypothetical protein | - |
D0812_RS06965 | 1476471..1476593 | + | 123 | WP_080772516.1 | DUF3265 domain-containing protein | - |
D0812_RS06970 | 1476634..1477143 | + | 510 | WP_047707023.1 | SMI1/KNR4 family protein | - |
D0812_RS06975 | 1477174..1477263 | + | 90 | WP_072609598.1 | DUF3265 domain-containing protein | - |
D0812_RS06980 | 1477301..1478554 | + | 1254 | WP_054824855.1 | hypothetical protein | - |
D0812_RS06985 | 1478569..1478661 | + | 93 | WP_194842420.1 | DUF3265 domain-containing protein | - |
D0812_RS06990 | 1478642..1479430 | + | 789 | WP_122044962.1 | hypothetical protein | - |
D0812_RS06995 | 1479445..1479537 | + | 93 | WP_194842409.1 | DUF3265 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 1474256..1526669 | 52413 | |
- | inside | Integron | - | - | 1472506..1489622 | 17116 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10891.57 Da Isoelectric Point: 4.3430
>T113237 WP_005398411.1 NZ_CP033137:c1474534-1474256 [Vibrio owensii]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD
Download Length: 279 bp
>T113237 NZ_CP033137:c1474534-1474256 [Vibrio owensii]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGTGTACAACGAGATGGTA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTATCTTACTGGGTTGAGGGCGATATCATCCGTGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACGGATTGA
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGTGTACAACGAGATGGTA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTATCTTACTGGGTTGAGGGCGATATCATCCGTGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACGGATTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 11000.29 Da Isoelectric Point: 8.0517
>AT113237 WP_054824926.1 NZ_CP033137:c1474815-1474531 [Vibrio owensii]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEESKARIRNRGKQ
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEESKARIRNRGKQ
Download Length: 285 bp
>AT113237 NZ_CP033137:c1474815-1474531 [Vibrio owensii]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGAAC
TCTAAGTGATGCTTGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCTGTTTTCGTTGAGCACCAAACTGCTAAGTCTCGA
ATGGAAGAGAGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGAAC
TCTAAGTGATGCTTGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCTGTTTTCGTTGAGCACCAAACTGCTAAGTCTCGA
ATGGAAGAGAGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A347UR22 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3G2PT85 |