Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 1824885..1825393 Replicon chromosome
Accession NZ_CP033133
Organism Acinetobacter wuhouensis strain WCHAW010062

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CDG68_RS11655 Protein ID WP_087551865.1
Coordinates 1824885..1825142 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag CDG68_RS11660 Protein ID WP_087551866.1
Coordinates 1825139..1825393 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDG68_RS11635 1820209..1820685 - 477 WP_087551862.1 internalin -
CDG68_RS11640 1820915..1822555 + 1641 WP_087551863.1 CTP synthase -
CDG68_RS11645 1822583..1823440 + 858 WP_087551864.1 3-deoxy-8-phosphooctulonate synthase -
CDG68_RS11650 1823505..1824794 + 1290 WP_068974291.1 phosphopyruvate hydratase -
CDG68_RS11655 1824885..1825142 - 258 WP_087551865.1 Txe/YoeB family addiction module toxin Toxin
CDG68_RS11660 1825139..1825393 - 255 WP_087551866.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CDG68_RS11665 1825709..1826095 + 387 WP_068974288.1 cell division protein FtsB -
CDG68_RS11670 1826061..1826777 + 717 WP_087551867.1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase -
CDG68_RS11675 1826877..1828013 + 1137 WP_068974286.1 rod shape-determining protein RodA -
CDG68_RS11680 1828267..1829535 + 1269 WP_087551868.1 D-amino acid dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10295.83 Da        Isoelectric Point: 8.8170

>T113228 WP_087551865.1 NZ_CP033133:c1825142-1824885 [Acinetobacter wuhouensis]
MILSWSNEAWEDYLYWQSTDKQILKRINTLIKDIKRSPFDGVGKPEPLKHDLSGYWSRRIDKENRIVYKVTTESIIIVMC
RYHYD

Download         Length: 258 bp

>T113228 NZ_CP033133:c1825142-1824885 [Acinetobacter wuhouensis]
ATGATTTTAAGTTGGAGCAATGAGGCTTGGGAAGATTACCTTTATTGGCAATCTACAGATAAACAAATACTCAAAAGAAT
TAATACATTGATAAAAGACATTAAACGATCACCATTTGATGGAGTTGGCAAACCAGAACCTCTCAAACATGATCTCAGTG
GTTATTGGTCAAGACGCATTGATAAAGAAAATCGTATCGTTTATAAAGTCACAACAGAATCAATTATTATTGTGATGTGC
CGTTATCATTATGATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9386.60 Da        Isoelectric Point: 5.0618

>AT113228 WP_087551866.1 NZ_CP033133:c1825393-1825139 [Acinetobacter wuhouensis]
MKVVTYSDLRKNLATVLDGVIDDHSPVLVTRQNNQTAVLISLEDFNAYEETAHLLKSPANAKRLRDSIAQIEAGKTINHE
LIEE

Download         Length: 255 bp

>AT113228 NZ_CP033133:c1825393-1825139 [Acinetobacter wuhouensis]
ATGAAAGTTGTTACATATTCGGATCTTCGTAAAAACTTAGCAACTGTATTAGATGGTGTCATTGATGATCATTCCCCTGT
ACTAGTGACTCGGCAAAATAATCAAACAGCCGTCTTGATCAGCTTAGAAGATTTTAATGCCTATGAAGAAACAGCCCATT
TGCTAAAAAGCCCTGCGAATGCAAAAAGATTGCGTGATTCAATTGCACAAATTGAAGCAGGTAAAACAATAAACCATGAG
CTGATTGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References