Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-paaA/RelE(toxin)
Location 801814..802264 Replicon chromosome
Accession NZ_CP033133
Organism Acinetobacter wuhouensis strain WCHAW010062

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CDG68_RS06635 Protein ID WP_087554542.1
Coordinates 801814..802089 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID -
Locus tag CDG68_RS06640 Protein ID WP_087554543.1
Coordinates 802076..802264 (-) Length 63 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDG68_RS06625 798702..800759 - 2058 WP_087554541.1 methionine--tRNA ligase -
CDG68_RS06630 800951..801781 + 831 WP_087554549.1 hypothetical protein -
CDG68_RS06635 801814..802089 - 276 WP_087554542.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CDG68_RS06640 802076..802264 - 189 WP_087554543.1 antitoxin Antitoxin
CDG68_RS06645 802458..802973 + 516 WP_087554544.1 hypothetical protein -
CDG68_RS06650 803028..803342 + 315 WP_087554545.1 antibiotic biosynthesis monooxygenase -
CDG68_RS06655 803353..803700 - 348 WP_087554546.1 hypothetical protein -
CDG68_RS06660 803690..803914 - 225 WP_087554547.1 hypothetical protein -
CDG68_RS06665 804135..804590 + 456 WP_004647755.1 helix-turn-helix domain-containing protein -
CDG68_RS06670 804580..805146 + 567 WP_108675453.1 IS630 family transposase -
CDG68_RS06675 805203..805391 + 189 WP_068974801.1 hypothetical protein -
CDG68_RS06680 805437..805736 - 300 WP_087553909.1 hypothetical protein -
CDG68_RS06685 805875..806171 + 297 WP_087553908.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10568.12 Da        Isoelectric Point: 4.7680

>T113227 WP_087554542.1 NZ_CP033133:c802089-801814 [Acinetobacter wuhouensis]
MLTVNWKINAVHDLEEIIDYIFIQNPEAAINLEDEILNTAESLADMPYSGRIGRVSGTRERIVHPNYMIIYQVLFDSIEI
LNIVHTKKHYP

Download         Length: 276 bp

>T113227 NZ_CP033133:c802089-801814 [Acinetobacter wuhouensis]
ATGTTGACCGTTAACTGGAAAATAAACGCTGTTCATGACTTAGAGGAAATTATTGATTATATTTTCATTCAAAACCCTGA
AGCCGCAATAAATCTCGAAGATGAAATTTTAAATACGGCTGAGAGCCTTGCTGATATGCCATACAGTGGGCGTATAGGTC
GAGTTTCTGGGACGAGAGAAAGGATCGTACATCCCAATTACATGATTATTTATCAGGTTTTATTTGATTCAATTGAAATT
CTCAATATCGTACATACAAAAAAGCATTATCCATAA

Antitoxin


Download         Length: 63 a.a.        Molecular weight: 7518.31 Da        Isoelectric Point: 4.4678

>AT113227 WP_087554543.1 NZ_CP033133:c802264-802076 [Acinetobacter wuhouensis]
MNEVFDAFVSEFDDADMEQNYNEWLKNKVEQSIVDSRPSISHDQVIERMKQKREERLKNVDR

Download         Length: 189 bp

>AT113227 NZ_CP033133:c802264-802076 [Acinetobacter wuhouensis]
ATGAATGAAGTATTTGATGCTTTCGTGTCAGAATTTGACGATGCGGATATGGAACAAAATTACAATGAATGGCTGAAAAA
CAAAGTTGAACAGTCTATTGTCGATTCACGCCCATCCATTTCACATGATCAAGTTATTGAACGCATGAAGCAAAAGCGCG
AAGAAAGATTAAAAAATGTTGACCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References