Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK(toxin)
Location 716020..716690 Replicon chromosome
Accession NZ_CP033107
Organism Plantibacter sp. PA-3-X8

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag EAO79_RS03450 Protein ID WP_124767799.1
Coordinates 716020..716367 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag EAO79_RS03455 Protein ID WP_206428278.1
Coordinates 716361..716690 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EAO79_RS03430 711828..712388 + 561 WP_079003723.1 Lrp/AsnC family transcriptional regulator -
EAO79_RS03435 712412..712795 - 384 WP_198425018.1 hypothetical protein -
EAO79_RS03440 712977..714389 + 1413 WP_124767798.1 aminopeptidase P N-terminal domain-containing protein -
EAO79_RS03445 714520..715998 + 1479 WP_124770051.1 SulP family inorganic anion transporter -
EAO79_RS03450 716020..716367 - 348 WP_124767799.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
EAO79_RS03455 716361..716690 - 330 WP_206428278.1 ribbon-helix-helix protein, CopG family Antitoxin
EAO79_RS03460 716820..717905 + 1086 WP_124767800.1 NYN domain-containing protein -
EAO79_RS03465 717997..719280 - 1284 WP_124767801.1 M18 family aminopeptidase -
EAO79_RS03470 719386..720708 + 1323 WP_124770052.1 LssY C-terminal domain-containing protein -
EAO79_RS03475 720705..721202 + 498 WP_124767802.1 DUF2809 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-112)

Antitoxin

Ribbon-helix-helix protein, CopG

(29-63)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12226.08 Da        Isoelectric Point: 8.7917

>T113180 WP_124767799.1 NZ_CP033107:c716367-716020 [Plantibacter sp. PA-3-X8]
MVIRRGDIRWVDIGPRERGGAPAGRRPVVVVQHDAYTRSALRTVIVAVVTSNTALAELPGNVFLPATASGLPKDSVVNTT
QLLTLDEDDLGPAAGRVPVTLSLDLDAGLRRVLHL

Download         Length: 348 bp

>T113180 NZ_CP033107:c716367-716020 [Plantibacter sp. PA-3-X8]
TTGGTGATCCGCCGCGGTGACATCCGGTGGGTCGATATCGGCCCTCGCGAACGGGGGGGTGCGCCCGCCGGTCGGCGCCC
GGTCGTCGTCGTCCAACATGACGCCTACACGCGGAGCGCACTCCGGACCGTGATCGTCGCGGTCGTCACATCGAACACGG
CGCTCGCCGAGCTCCCGGGCAACGTGTTCCTCCCTGCGACGGCTTCCGGCCTGCCGAAGGACTCGGTCGTGAACACCACG
CAGCTGCTCACCCTCGATGAGGACGACCTCGGTCCGGCCGCCGGAAGGGTGCCCGTCACCCTGTCACTGGATCTGGACGC
GGGGCTCCGGCGAGTGCTGCACCTCTGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 11454.75 Da        Isoelectric Point: 4.3943

>AT113180 WP_206428278.1 NZ_CP033107:c716690-716361 [Plantibacter sp. PA-3-X8]
MPSHAVDIFSPGSQPKLYPVILSPVKTAISLPDELFTRVEARAAELGVNRSEFFAAAASRYLDETDAAGLTDAVDTALRH
AGVASAEEARGVAAAGRDRLAELTAGDDW

Download         Length: 330 bp

>AT113180 NZ_CP033107:c716690-716361 [Plantibacter sp. PA-3-X8]
ATGCCCAGTCACGCCGTCGACATCTTCAGCCCAGGGTCGCAACCCAAGTTATACCCGGTTATACTCTCACCTGTGAAGAC
CGCCATCTCGTTGCCCGATGAACTGTTCACCCGCGTCGAGGCTCGCGCCGCCGAGCTCGGTGTCAACCGGTCCGAGTTCT
TCGCGGCGGCGGCGAGTCGGTATCTCGACGAGACCGATGCCGCCGGTCTCACTGACGCAGTGGACACCGCGCTGCGGCAT
GCGGGAGTCGCTTCGGCGGAGGAAGCACGGGGCGTCGCCGCGGCCGGACGCGACCGCCTTGCCGAACTCACTGCCGGAGA
CGATTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References