Detailed information of TA system TA113179

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN(toxin)
• Location: 388704..389389
• Replicon: chromosome
• Accession: NZ_CP033107
• Organism: Plantibacter sp. PA-3-X8

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: EAO79_RS01900
• Protein ID: WP_124767584.1
• Coordinates: 388943..389389 (+)
• Length: 149 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: EAO79_RS01895
• Protein ID: WP_124767583.1
• Coordinates: 388704..388946 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EAO79_RS01880	384969..385637	+	669	WP_124767581.1	GntR family transcriptional regulator	-
EAO79_RS01885	385758..386720	-	963	WP_086475276.1	prephenate dehydratase	-
EAO79_RS01890	387010..388578	+	1569	WP_124767582.1	hypothetical protein	-
EAO79_RS01895	388704..388946	+	243	WP_124767583.1	ribbon-helix-helix protein, CopG family	Antitoxin
EAO79_RS01900	388943..389389	+	447	WP_124767584.1	type II toxin-antitoxin system VapC family toxin	Toxin
EAO79_RS01905	389418..391037	+	1620	WP_079706448.1	phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)	-
EAO79_RS01910	391194..391964	-	771	WP_124770028.1	M15 family metallopeptidase	-
EAO79_RS01915	392127..393221	+	1095	WP_124767585.1	alpha/beta hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-133)

Antitoxin

• Ribbon-helix-helix protein, CopG (2-38)

Sequences

Toxin

Protein

• Length: 149 a.a.
• Molecular weight: 16355.62 Da
• Isoelectric Point: 6.4827

>T113179 WP_124767584.1 NZ_CP033107:388943-389389 [Plantibacter sp. PA-3-X8]
VKVVDTNVLIGAFRPDSQHHRTLATWLEDAVRSREPLGVSEAVLAGYIRIVTQRRIFVDPTPISIALEQMQRLRDEPGVQ
VVRPGPSFWTVFTSLCAAVEAQGNLVSDAAHAALAIEHRATFVTLDRDFARFPDLRWESPLATGQAPS

Nucleotide

• Length: 447 bp

>T113179 NZ_CP033107:388943-389389 [Plantibacter sp. PA-3-X8]
GTGAAGGTGGTCGACACCAACGTCCTCATCGGCGCGTTCCGACCCGATTCACAACACCACCGCACGCTCGCAACCTGGTT
GGAAGATGCCGTCCGATCGAGAGAACCCCTGGGCGTCAGCGAAGCCGTGCTCGCGGGGTACATCCGGATCGTGACCCAGC
GTCGGATCTTCGTCGATCCCACTCCGATCTCCATCGCGCTCGAGCAGATGCAGCGACTCCGCGACGAGCCCGGCGTTCAG
GTCGTCCGCCCTGGCCCGTCGTTCTGGACGGTCTTCACCTCGCTCTGTGCAGCGGTCGAGGCCCAAGGCAACCTCGTCTC
GGACGCGGCCCACGCCGCACTCGCGATCGAACACCGGGCCACCTTCGTCACGCTCGATCGCGACTTCGCGCGCTTCCCCG
ACCTCCGCTGGGAATCGCCACTCGCCACGGGTCAAGCGCCTTCCTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8764.80 Da
• Isoelectric Point: 4.4621

>AT113179 WP_124767583.1 NZ_CP033107:388704-388946 [Plantibacter sp. PA-3-X8]
MRTTIRLADEFYEAVREHASQEGKTVTAYIEEALRAKLAAAAAPPEREPYKVVPYGGGGPRPGIDLTNNAQLEDIMDGFE

Nucleotide

• Length: 243 bp

>AT113179 NZ_CP033107:388704-388946 [Plantibacter sp. PA-3-X8]
ATGCGAACGACCATCCGACTCGCCGACGAGTTCTACGAGGCCGTCCGCGAGCACGCCTCGCAGGAGGGGAAGACCGTCAC
CGCCTACATCGAAGAGGCCCTGCGCGCGAAGCTGGCCGCAGCGGCCGCGCCGCCCGAGCGGGAACCCTACAAGGTCGTGC
CGTACGGCGGGGGAGGACCCCGCCCAGGAATCGACCTCACGAACAACGCGCAACTCGAGGACATCATGGACGGTTTCGAG
TGA