Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 2957920..2958548 Replicon chromosome
Accession NZ_CP033106
Organism Pantoea sp. 201603H

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag EAE31_RS13560 Protein ID WP_128179335.1
Coordinates 2958330..2958548 (+) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag EAE31_RS13555 Protein ID WP_128179336.1
Coordinates 2957920..2958300 (+) Length 127 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EAE31_RS13525 2953734..2953988 + 255 WP_154325244.1 type B 50S ribosomal protein L31 -
EAE31_RS13530 2954001..2954141 + 141 WP_128179340.1 type B 50S ribosomal protein L36 -
EAE31_RS13535 2954188..2955066 - 879 WP_154325245.1 metal ABC transporter substrate-binding protein -
EAE31_RS13540 2955063..2955932 - 870 WP_128179440.1 metal ABC transporter permease -
EAE31_RS13545 2955935..2956621 - 687 WP_128179338.1 ATP-binding cassette domain-containing protein -
EAE31_RS13550 2957165..2957518 + 354 WP_128179337.1 hypothetical protein -
EAE31_RS13555 2957920..2958300 + 381 WP_128179336.1 Hha toxicity modulator TomB Antitoxin
EAE31_RS13560 2958330..2958548 + 219 WP_128179335.1 hemolysin expression modulator Hha Toxin
EAE31_RS13570 2959374..2959685 + 312 WP_128179334.1 MGMT family protein -
EAE31_RS13575 2959785..2960342 - 558 WP_128179333.1 YbaY family lipoprotein -
EAE31_RS13580 2960515..2961447 - 933 WP_154325246.1 LysR family transcriptional regulator -
EAE31_RS13585 2961559..2962761 + 1203 WP_154325247.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8655.97 Da        Isoelectric Point: 7.9893

>T113178 WP_128179335.1 NZ_CP033106:2958330-2958548 [Pantoea sp. 201603H]
MTDKTLTKTDYLMRLRRCRSIDTLERVIEKNKYELSDDELEVFNSAADHRLAELTMNKLYDKVPVSVWKYVR

Download         Length: 219 bp

>T113178 NZ_CP033106:2958330-2958548 [Pantoea sp. 201603H]
ATGACTGACAAGACTCTTACTAAAACTGATTATCTAATGCGCTTAAGACGTTGTCGCTCGATTGACACGCTTGAACGAGT
GATTGAAAAAAATAAATATGAATTATCTGATGATGAATTAGAAGTATTCAATTCCGCAGCGGACCACCGTCTGGCTGAGC
TAACAATGAATAAACTCTATGACAAAGTCCCCGTTTCCGTATGGAAATATGTTCGCTAG

Antitoxin


Download         Length: 127 a.a.        Molecular weight: 14656.42 Da        Isoelectric Point: 4.4796

>AT113178 WP_128179336.1 NZ_CP033106:2957920-2958300 [Pantoea sp. 201603H]
MDEYSPKRHDIAQLKFLCENLYDESMTTLGDSHHGWVNDPTSAINLQLNELIEHIASFTMNYKIKHVEDSDLIGQIDEYL
DDTFMLFSNYGINAQDLNRWQKSAKRLFNIFAEECALLPLQPSHSF

Download         Length: 381 bp

>AT113178 NZ_CP033106:2957920-2958300 [Pantoea sp. 201603H]
ATGGACGAATATTCACCGAAAAGGCATGATATTGCCCAATTGAAATTCCTGTGTGAAAATCTGTATGACGAAAGCATGAC
GACCCTCGGGGATAGTCATCACGGATGGGTGAACGATCCGACTTCTGCAATCAACCTGCAACTGAACGAACTGATTGAAC
ATATCGCCTCATTCACCATGAATTACAAAATCAAACACGTTGAAGATAGTGACCTGATTGGCCAAATCGATGAGTACCTT
GACGATACTTTTATGTTGTTTAGCAATTACGGTATTAATGCTCAAGATCTCAATCGTTGGCAAAAATCAGCAAAACGTCT
TTTTAACATTTTTGCTGAAGAGTGTGCTCTTCTACCGTTGCAACCGAGCCATTCGTTTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References