Detailed information of TA system TA113165

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-YefM
• Location: 5434281..5434954
• Replicon: chromosome
• Accession: NZ_CP033105
• Organism: Pseudomonas sp. LTJR-52

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: EAW52_RS25265
• Protein ID: WP_122044584.1
• Coordinates: 5434281..5434703 (-)
• Length: 141 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: EAW52_RS25270
• Protein ID: WP_122044585.1
• Coordinates: 5434703..5434954 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EAW52_RS25240	5429855..5430373	-	519	WP_122044580.1	hypothetical protein	-
EAW52_RS25245	5430456..5430704	-	249	WP_122044581.1	hypothetical protein	-
EAW52_RS25250	5430790..5432373	-	1584	WP_122044582.1	exodeoxyribonuclease VII large subunit	-
EAW52_RS25255	5432375..5432590	-	216	WP_122044583.1	exodeoxyribonuclease VII small subunit	-
EAW52_RS25260	5432739..5433883	-	1145	Protein_4948	IS200/IS605 family element transposase accessory protein TnpB	-
EAW52_RS25265	5434281..5434703	-	423	WP_122044584.1	type II toxin-antitoxin system VapC family toxin	Toxin
EAW52_RS25270	5434703..5434954	-	252	WP_122044585.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
EAW52_RS25275	5435183..5435398	-	216	WP_122044586.1	hypothetical protein	-
EAW52_RS25285	5437058..5437652	-	595	Protein_4952	transposase	-
EAW52_RS25290	5438197..5438556	-	360	WP_122044588.1	Rieske (2Fe-2S) protein	-
EAW52_RS25295	5438560..5439501	-	942	WP_122044589.1	VOC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	5432739..5437447	4708

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-122)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (3-62)

Sequences

Toxin

Protein

• Length: 141 a.a.
• Molecular weight: 15377.81 Da
• Isoelectric Point: 6.7192

>T113165 WP_122044584.1 NZ_CP033105:c5434703-5434281 [Pseudomonas sp. LTJR-52]
MFLLDTNVVSELRKAKLGKANAQVVSWAKSVQAGELYLSSISVLEIEQGILQYERRDPIQGAVLRSWLEQHVLPGFAGRI
LPVDTAVAIQCARLHVPDPRSERDALIAASALVHGMTVVTRNVKDFEPTGVPILDPWQAI

Nucleotide

• Length: 423 bp

>T113165 NZ_CP033105:c5434703-5434281 [Pseudomonas sp. LTJR-52]
ATGTTCTTGCTTGATACTAATGTTGTATCCGAACTTCGCAAGGCCAAGCTGGGTAAAGCAAATGCACAGGTAGTGTCCTG
GGCGAAAAGCGTACAAGCCGGGGAACTCTATCTCTCATCTATATCTGTTCTGGAAATTGAACAAGGGATTTTGCAATATG
AGCGCAGGGATCCCATTCAAGGAGCTGTCTTGCGGTCATGGTTGGAACAGCATGTTCTTCCCGGCTTTGCAGGACGTATC
CTACCTGTAGACACAGCTGTTGCTATACAATGTGCACGACTGCATGTACCCGACCCCAGAAGCGAGCGTGACGCCCTTAT
TGCTGCCTCAGCGCTAGTACATGGGATGACGGTGGTGACTCGTAACGTAAAGGACTTTGAACCAACAGGCGTTCCAATTC
TTGATCCATGGCAGGCTATCTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9350.64 Da
• Isoelectric Point: 7.2033

>AT113165 WP_122044585.1 NZ_CP033105:c5434954-5434703 [Pseudomonas sp. LTJR-52]
MPTTVSSRQFNHDTSGAKKAALRGPVFITDRGKPAHVLLSIEEYQRLTRTQISIIDILAMPNDEDLEFEAPRTVIRTRNV
DLS

Nucleotide

• Length: 252 bp

>AT113165 NZ_CP033105:c5434954-5434703 [Pseudomonas sp. LTJR-52]
ATGCCTACTACTGTATCAAGCCGACAGTTCAACCACGACACCAGTGGAGCTAAGAAGGCTGCATTGAGGGGTCCTGTCTT
CATCACAGATCGTGGTAAACCTGCCCATGTTTTGTTAAGTATTGAGGAATATCAGCGCCTGACACGCACCCAAATCAGCA
TCATAGATATACTTGCCATGCCCAACGATGAAGATCTGGAGTTCGAGGCACCCCGGACAGTAATTCGTACGCGGAATGTG
GATCTTTCCTGA