Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-RelB |
Location | 1535678..1536194 | Replicon | chromosome |
Accession | NZ_CP033104 | ||
Organism | Pseudomonas sp. LTGT-11-2Z |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A3G2HKE7 |
Locus tag | D8767_RS07020 | Protein ID | WP_016712032.1 |
Coordinates | 1535907..1536194 (+) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A446A2J5 |
Locus tag | D8767_RS07015 | Protein ID | WP_028700126.1 |
Coordinates | 1535678..1535917 (+) | Length | 80 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
D8767_RS06995 | 1530924..1531895 | - | 972 | WP_063977227.1 | TRAP transporter substrate-binding protein | - |
D8767_RS07000 | 1531961..1532842 | - | 882 | WP_016712036.1 | SMP-30/gluconolactonase/LRE family protein | - |
D8767_RS07005 | 1532869..1533675 | - | 807 | WP_122048289.1 | NAD(P)-dependent oxidoreductase | - |
D8767_RS07010 | 1533839..1535077 | - | 1239 | WP_016712034.1 | OprD family porin | - |
D8767_RS07015 | 1535678..1535917 | + | 240 | WP_028700126.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
D8767_RS07020 | 1535907..1536194 | + | 288 | WP_016712032.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
D8767_RS07025 | 1536308..1537558 | - | 1251 | WP_016712031.1 | ribonucleotide-diphosphate reductase subunit beta | - |
D8767_RS07030 | 1538276..1541155 | - | 2880 | WP_016712029.1 | ribonucleoside-diphosphate reductase subunit alpha | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11233.07 Da Isoelectric Point: 9.9006
>T113161 WP_016712032.1 NZ_CP033104:1535907-1536194 [Pseudomonas sp. LTGT-11-2Z]
MTYSLDFDCRALKEWKKLGDTVREQFKKKLAEVLLNPRVEANRLHSLPDCYKIKLRSSGYRLVYQVIGQEIVVFVVAVDR
RERDQAYKKAAERLE
MTYSLDFDCRALKEWKKLGDTVREQFKKKLAEVLLNPRVEANRLHSLPDCYKIKLRSSGYRLVYQVIGQEIVVFVVAVDR
RERDQAYKKAAERLE
Download Length: 288 bp
>T113161 NZ_CP033104:1535907-1536194 [Pseudomonas sp. LTGT-11-2Z]
ATGACCTATAGCCTCGACTTCGATTGCCGCGCATTGAAAGAGTGGAAGAAGCTGGGCGATACAGTGCGTGAGCAGTTCAA
GAAGAAACTGGCAGAGGTCTTGCTCAATCCTCGAGTCGAGGCAAACCGCCTTCACTCGCTGCCAGATTGCTACAAAATCA
AGCTTCGCAGCAGTGGGTACAGGCTGGTCTATCAGGTCATTGGCCAAGAGATCGTGGTTTTTGTCGTTGCTGTTGATCGC
CGTGAACGGGACCAAGCTTACAAAAAGGCTGCTGAGCGGCTTGAATAG
ATGACCTATAGCCTCGACTTCGATTGCCGCGCATTGAAAGAGTGGAAGAAGCTGGGCGATACAGTGCGTGAGCAGTTCAA
GAAGAAACTGGCAGAGGTCTTGCTCAATCCTCGAGTCGAGGCAAACCGCCTTCACTCGCTGCCAGATTGCTACAAAATCA
AGCTTCGCAGCAGTGGGTACAGGCTGGTCTATCAGGTCATTGGCCAAGAGATCGTGGTTTTTGTCGTTGCTGTTGATCGC
CGTGAACGGGACCAAGCTTACAAAAAGGCTGCTGAGCGGCTTGAATAG
Antitoxin
Download Length: 80 a.a. Molecular weight: 9111.46 Da Isoelectric Point: 4.6310
>AT113161 WP_028700126.1 NZ_CP033104:1535678-1535917 [Pseudomonas sp. LTGT-11-2Z]
MASINIRVDDDLKARAYKELERLGVTPSELMRQALQYVAERGKLPFRPVLMTEEDEDLIATVQERLASPQRVRVQLDDL
MASINIRVDDDLKARAYKELERLGVTPSELMRQALQYVAERGKLPFRPVLMTEEDEDLIATVQERLASPQRVRVQLDDL
Download Length: 240 bp
>AT113161 NZ_CP033104:1535678-1535917 [Pseudomonas sp. LTGT-11-2Z]
ATGGCTTCCATCAATATCCGCGTCGACGACGATCTCAAAGCTCGCGCCTACAAAGAGCTTGAGCGTCTTGGTGTAACCCC
CTCCGAACTCATGCGCCAAGCCCTGCAATATGTAGCTGAGCGGGGCAAGCTACCCTTCCGGCCGGTCCTGATGACCGAGG
AAGATGAAGACCTCATTGCCACTGTACAAGAGAGGCTTGCTTCCCCGCAGCGCGTGAGGGTTCAGCTGGATGACCTATAG
ATGGCTTCCATCAATATCCGCGTCGACGACGATCTCAAAGCTCGCGCCTACAAAGAGCTTGAGCGTCTTGGTGTAACCCC
CTCCGAACTCATGCGCCAAGCCCTGCAATATGTAGCTGAGCGGGGCAAGCTACCCTTCCGGCCGGTCCTGATGACCGAGG
AAGATGAAGACCTCATTGCCACTGTACAAGAGAGGCTTGCTTCCCCGCAGCGCGTGAGGGTTCAGCTGGATGACCTATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3G2HKE7 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A446A2J5 |