Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1535678..1536194 Replicon chromosome
Accession NZ_CP033104
Organism Pseudomonas sp. LTGT-11-2Z

Toxin (Protein)


Gene name relE Uniprot ID A0A3G2HKE7
Locus tag D8767_RS07020 Protein ID WP_016712032.1
Coordinates 1535907..1536194 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A446A2J5
Locus tag D8767_RS07015 Protein ID WP_028700126.1
Coordinates 1535678..1535917 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8767_RS06995 1530924..1531895 - 972 WP_063977227.1 TRAP transporter substrate-binding protein -
D8767_RS07000 1531961..1532842 - 882 WP_016712036.1 SMP-30/gluconolactonase/LRE family protein -
D8767_RS07005 1532869..1533675 - 807 WP_122048289.1 NAD(P)-dependent oxidoreductase -
D8767_RS07010 1533839..1535077 - 1239 WP_016712034.1 OprD family porin -
D8767_RS07015 1535678..1535917 + 240 WP_028700126.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
D8767_RS07020 1535907..1536194 + 288 WP_016712032.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D8767_RS07025 1536308..1537558 - 1251 WP_016712031.1 ribonucleotide-diphosphate reductase subunit beta -
D8767_RS07030 1538276..1541155 - 2880 WP_016712029.1 ribonucleoside-diphosphate reductase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-79)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11233.07 Da        Isoelectric Point: 9.9006

>T113161 WP_016712032.1 NZ_CP033104:1535907-1536194 [Pseudomonas sp. LTGT-11-2Z]
MTYSLDFDCRALKEWKKLGDTVREQFKKKLAEVLLNPRVEANRLHSLPDCYKIKLRSSGYRLVYQVIGQEIVVFVVAVDR
RERDQAYKKAAERLE

Download         Length: 288 bp

>T113161 NZ_CP033104:1535907-1536194 [Pseudomonas sp. LTGT-11-2Z]
ATGACCTATAGCCTCGACTTCGATTGCCGCGCATTGAAAGAGTGGAAGAAGCTGGGCGATACAGTGCGTGAGCAGTTCAA
GAAGAAACTGGCAGAGGTCTTGCTCAATCCTCGAGTCGAGGCAAACCGCCTTCACTCGCTGCCAGATTGCTACAAAATCA
AGCTTCGCAGCAGTGGGTACAGGCTGGTCTATCAGGTCATTGGCCAAGAGATCGTGGTTTTTGTCGTTGCTGTTGATCGC
CGTGAACGGGACCAAGCTTACAAAAAGGCTGCTGAGCGGCTTGAATAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9111.46 Da        Isoelectric Point: 4.6310

>AT113161 WP_028700126.1 NZ_CP033104:1535678-1535917 [Pseudomonas sp. LTGT-11-2Z]
MASINIRVDDDLKARAYKELERLGVTPSELMRQALQYVAERGKLPFRPVLMTEEDEDLIATVQERLASPQRVRVQLDDL

Download         Length: 240 bp

>AT113161 NZ_CP033104:1535678-1535917 [Pseudomonas sp. LTGT-11-2Z]
ATGGCTTCCATCAATATCCGCGTCGACGACGATCTCAAAGCTCGCGCCTACAAAGAGCTTGAGCGTCTTGGTGTAACCCC
CTCCGAACTCATGCGCCAAGCCCTGCAATATGTAGCTGAGCGGGGCAAGCTACCCTTCCGGCCGGTCCTGATGACCGAGG
AAGATGAAGACCTCATTGCCACTGTACAAGAGAGGCTTGCTTCCCCGCAGCGCGTGAGGGTTCAGCTGGATGACCTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2HKE7

Antitoxin

Source ID Structure
AlphaFold DB A0A446A2J5

References