Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1960261..1960532 Replicon chromosome
Accession NZ_CP033096
Organism Escherichia coli strain CP53

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1960391..1960494 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1960261..1960532 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EAH50_RS11700 1956816..1957478 - 663 WP_000944256.1 exodeoxyribonuclease X -
EAH50_RS11705 1957502..1958158 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EAH50_RS11710 1958260..1958490 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EAH50_RS11715 1958629..1959003 + 375 WP_000255065.1 CopC domain-containing protein YobA -
EAH50_RS11720 1959007..1959879 + 873 WP_000879298.1 copper homeostasis membrane protein CopD -
EAH50_RS11725 1959892..1960233 + 342 WP_000976472.1 YebY family protein -
- 1960261..1960532 - 272 - - Antitoxin
- 1960391..1960494 + 104 - - Toxin
EAH50_RS11730 1960629..1961285 + 657 WP_096178143.1 protein-serine/threonine phosphatase -
EAH50_RS11735 1961286..1961477 - 192 WP_001338167.1 YebW family protein -
EAH50_RS11740 1961582..1961818 - 237 WP_001338166.1 DUF1480 family protein -
EAH50_RS11745 1961936..1963375 - 1440 WP_024238487.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T113117 NZ_CP033096:1960391-1960494 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT113117 NZ_CP033096:c1960532-1960261 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References