Detailed information of TA system TA113072

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yoeB-relB/YoeB-YefM
• Location: 3510643..3511149
• Replicon: chromosome
• Accession: NZ_CP033081
• Organism: Glutamicibacter nicotianae strain OTC-16

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: D3647_RS16335
• Protein ID: WP_121867655.1
• Coordinates: 3510895..3511149 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: D3647_RS16330
• Protein ID: WP_121867654.1
• Coordinates: 3510643..3510894 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D3647_RS16310	3506221..3507459	+	1239	WP_052253958.1	CoA transferase	-
D3647_RS16315	3507515..3507871	+	357	WP_198934360.1	acyl-CoA thioesterase	-
D3647_RS16320	3507881..3509095	+	1215	WP_038992863.1	acyl-CoA dehydrogenase family protein	-
D3647_RS16325	3509232..3510287	+	1056	WP_121867653.1	GTP-binding protein	-
D3647_RS16330	3510643..3510894	+	252	WP_121867654.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
D3647_RS16335	3510895..3511149	+	255	WP_121867655.1	Txe/YoeB family addiction module toxin	Toxin
D3647_RS16340	3511145..3511372	+	228	WP_121867656.1	hypothetical protein	-
D3647_RS16345	3511276..3511635	+	360	WP_162989387.1	hypothetical protein	-
D3647_RS16350	3512504..3513340	-	837	WP_121867657.1	(S)-ureidoglycine aminohydrolase	-
D3647_RS16355	3513351..3514604	-	1254	WP_121867658.1	aldolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (2-69)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10126.49 Da
• Isoelectric Point: 6.2185

>T113072 WP_121867655.1 NZ_CP033081:3510895-3511149 [Glutamicibacter nicotianae]
VRLVWDRAGWDDYVHWQTADRRVIKRVNTLIEACLPDPFQGIEKPEQLKYGASDSWSRRITDEHRLVYIVIEEDLIILQA
RYHY

Nucleotide

• Length: 255 bp

>T113072 NZ_CP033081:3510895-3511149 [Glutamicibacter nicotianae]
GTGCGGCTCGTCTGGGATCGGGCAGGATGGGACGACTACGTCCACTGGCAAACGGCCGACCGGCGCGTTATCAAGAGAGT
CAACACCTTGATCGAAGCATGCCTTCCGGATCCCTTCCAAGGGATTGAAAAGCCCGAACAGCTGAAATACGGGGCCTCCG
ACTCATGGTCCCGTCGGATTACCGACGAACACCGACTGGTCTACATCGTGATCGAAGAAGACTTGATCATCCTTCAAGCC
CGATACCACTATTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9429.48 Da
• Isoelectric Point: 4.6412

>AT113072 WP_121867654.1 NZ_CP033081:3510643-3510894 [Glutamicibacter nicotianae]
MSISASEARKTLFPLIEQVNDDRQAVEIVSRKGNAVLMAADEYAAWQETAYLFRSPANARRLLDAYERARSGITETHELD
RDE

Nucleotide

• Length: 252 bp

>AT113072 NZ_CP033081:3510643-3510894 [Glutamicibacter nicotianae]
ATGTCCATCAGTGCAAGCGAAGCCCGCAAGACGCTCTTTCCATTGATTGAACAAGTCAACGATGATCGCCAAGCTGTCGA
AATCGTGTCACGCAAGGGAAATGCTGTTCTCATGGCAGCAGATGAATACGCAGCATGGCAAGAGACCGCGTACCTCTTCC
GCTCGCCAGCCAATGCCCGGCGGCTCTTGGATGCCTACGAACGTGCACGGTCGGGAATAACAGAGACCCACGAGCTCGAC
CGGGACGAATAA