Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 3510643..3511149 Replicon chromosome
Accession NZ_CP033081
Organism Glutamicibacter nicotianae strain OTC-16

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag D3647_RS16335 Protein ID WP_121867655.1
Coordinates 3510895..3511149 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D3647_RS16330 Protein ID WP_121867654.1
Coordinates 3510643..3510894 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D3647_RS16310 3506221..3507459 + 1239 WP_052253958.1 CoA transferase -
D3647_RS16315 3507515..3507871 + 357 WP_198934360.1 acyl-CoA thioesterase -
D3647_RS16320 3507881..3509095 + 1215 WP_038992863.1 acyl-CoA dehydrogenase family protein -
D3647_RS16325 3509232..3510287 + 1056 WP_121867653.1 GTP-binding protein -
D3647_RS16330 3510643..3510894 + 252 WP_121867654.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
D3647_RS16335 3510895..3511149 + 255 WP_121867655.1 Txe/YoeB family addiction module toxin Toxin
D3647_RS16340 3511145..3511372 + 228 WP_121867656.1 hypothetical protein -
D3647_RS16345 3511276..3511635 + 360 WP_162989387.1 hypothetical protein -
D3647_RS16350 3512504..3513340 - 837 WP_121867657.1 (S)-ureidoglycine aminohydrolase -
D3647_RS16355 3513351..3514604 - 1254 WP_121867658.1 aldolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-69)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10126.49 Da        Isoelectric Point: 6.2185

>T113072 WP_121867655.1 NZ_CP033081:3510895-3511149 [Glutamicibacter nicotianae]
VRLVWDRAGWDDYVHWQTADRRVIKRVNTLIEACLPDPFQGIEKPEQLKYGASDSWSRRITDEHRLVYIVIEEDLIILQA
RYHY

Download         Length: 255 bp

>T113072 NZ_CP033081:3510895-3511149 [Glutamicibacter nicotianae]
GTGCGGCTCGTCTGGGATCGGGCAGGATGGGACGACTACGTCCACTGGCAAACGGCCGACCGGCGCGTTATCAAGAGAGT
CAACACCTTGATCGAAGCATGCCTTCCGGATCCCTTCCAAGGGATTGAAAAGCCCGAACAGCTGAAATACGGGGCCTCCG
ACTCATGGTCCCGTCGGATTACCGACGAACACCGACTGGTCTACATCGTGATCGAAGAAGACTTGATCATCCTTCAAGCC
CGATACCACTATTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9429.48 Da        Isoelectric Point: 4.6412

>AT113072 WP_121867654.1 NZ_CP033081:3510643-3510894 [Glutamicibacter nicotianae]
MSISASEARKTLFPLIEQVNDDRQAVEIVSRKGNAVLMAADEYAAWQETAYLFRSPANARRLLDAYERARSGITETHELD
RDE

Download         Length: 252 bp

>AT113072 NZ_CP033081:3510643-3510894 [Glutamicibacter nicotianae]
ATGTCCATCAGTGCAAGCGAAGCCCGCAAGACGCTCTTTCCATTGATTGAACAAGTCAACGATGATCGCCAAGCTGTCGA
AATCGTGTCACGCAAGGGAAATGCTGTTCTCATGGCAGCAGATGAATACGCAGCATGGCAAGAGACCGCGTACCTCTTCC
GCTCGCCAGCCAATGCCCGGCGGCTCTTGGATGCCTACGAACGTGCACGGTCGGGAATAACAGAGACCCACGAGCTCGAC
CGGGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References