Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 4452549..4453106 Replicon chromosome
Accession NZ_CP033076
Organism Buttiauxella sp. 3AFRM03

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D8682_RS22195 Protein ID WP_121815150.1
Coordinates 4452549..4452824 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D8682_RS22200 Protein ID WP_121815151.1
Coordinates 4452825..4453106 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8682_RS22170 4447624..4448556 + 933 WP_121815147.1 PDR/VanB family oxidoreductase -
D8682_RS22175 4448567..4449061 + 495 WP_121815148.1 flavin reductase -
D8682_RS22180 4449106..4450446 + 1341 WP_064544670.1 MHS family MFS transporter -
D8682_RS22185 4450430..4451545 + 1116 WP_064544672.1 muconate/chloromuconate family cycloisomerase -
D8682_RS22190 4451579..4452505 + 927 WP_121815149.1 catechol 1,2-dioxygenase -
D8682_RS22195 4452549..4452824 - 276 WP_121815150.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D8682_RS22200 4452825..4453106 - 282 WP_121815151.1 ribbon-helix-helix protein, CopG family Antitoxin
D8682_RS22205 4453212..4453643 - 432 WP_083963319.1 hypothetical protein -
D8682_RS22210 4454472..4455044 + 573 WP_121815152.1 lysozyme -
D8682_RS22215 4455255..4455785 + 531 WP_121815153.1 hypothetical protein -
D8682_RS22220 4456072..4456611 - 540 WP_121815154.1 DUF2058 domain-containing protein -
D8682_RS22225 4456860..4457090 + 231 WP_064544679.1 hypothetical protein -
D8682_RS22230 4457114..4458040 - 927 WP_121815155.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-45)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10667.34 Da        Isoelectric Point: 8.5634

>T113065 WP_121815150.1 NZ_CP033076:c4452824-4452549 [Buttiauxella sp. 3AFRM03]
MQVFWTDHALQDLDRLHAFLAKANAEAAAHVLQSLVVAPANLLTYSRMGPMLEKYEPREVRRLIVGSYEMHYELKVNSLH
ILRVWHTRENR

Download         Length: 276 bp

>T113065 NZ_CP033076:c4452824-4452549 [Buttiauxella sp. 3AFRM03]
ATGCAGGTTTTCTGGACCGATCACGCATTGCAGGATCTAGATCGGCTCCATGCCTTTCTTGCTAAAGCCAATGCAGAAGC
GGCCGCACACGTTCTTCAATCATTGGTGGTTGCTCCAGCAAATTTACTAACATACTCACGCATGGGACCGATGCTGGAAA
AATATGAGCCACGCGAAGTACGCCGTCTGATTGTTGGCAGCTATGAAATGCACTATGAACTCAAGGTTAATTCGCTGCAT
ATTCTGCGGGTATGGCATACGCGAGAAAATAGATAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10613.04 Da        Isoelectric Point: 5.6227

>AT113065 WP_121815151.1 NZ_CP033076:c4453106-4452825 [Buttiauxella sp. 3AFRM03]
MGQSQTRVITAHIPVEMAEKIDELAANYDRSRGWIVKQALAAIIEQEESRHQMILQGMQDVDEGRVVEHADVMKWVNSLN
TETPLTTPQSRRK

Download         Length: 282 bp

>AT113065 NZ_CP033076:c4453106-4452825 [Buttiauxella sp. 3AFRM03]
ATGGGACAATCACAAACCAGAGTTATTACCGCTCATATACCCGTTGAGATGGCTGAAAAAATCGATGAACTGGCAGCAAA
TTATGACCGCTCTCGTGGCTGGATAGTTAAGCAGGCATTGGCCGCGATCATTGAGCAGGAAGAAAGCCGTCATCAGATGA
TTTTGCAAGGGATGCAGGATGTTGACGAAGGGCGTGTGGTTGAACATGCTGATGTCATGAAATGGGTAAACAGTCTGAAC
ACTGAAACCCCACTCACAACACCTCAATCCAGGCGCAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References