Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3874521..3875190 Replicon chromosome
Accession NZ_CP033076
Organism Buttiauxella sp. 3AFRM03

Toxin (Protein)


Gene name cptA Uniprot ID A0A3G2IIE9
Locus tag D8682_RS19600 Protein ID WP_064543659.1
Coordinates 3874768..3875190 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1B7I271
Locus tag D8682_RS19595 Protein ID WP_064513590.1
Coordinates 3874521..3874787 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D8682_RS19575 3870698..3871381 - 684 WP_121814933.1 DUF4875 domain-containing protein -
D8682_RS19580 3871582..3872310 - 729 WP_121814934.1 MurR/RpiR family transcriptional regulator -
D8682_RS19585 3872482..3873135 + 654 WP_064543654.1 hemolysin III family protein -
D8682_RS19590 3873287..3874273 - 987 WP_064543657.1 tRNA-modifying protein YgfZ -
D8682_RS19595 3874521..3874787 + 267 WP_064513590.1 FAD assembly factor SdhE Antitoxin
D8682_RS19600 3874768..3875190 + 423 WP_064543659.1 protein YgfX Toxin
D8682_RS19605 3875198..3875719 - 522 WP_064543777.1 flavodoxin FldB -
D8682_RS19610 3875833..3876729 + 897 WP_074388528.1 site-specific tyrosine recombinase XerD -
D8682_RS19615 3876754..3877470 + 717 WP_064543661.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
D8682_RS19620 3877478..3879211 + 1734 WP_121814935.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16644.59 Da        Isoelectric Point: 11.2010

>T113064 WP_064543659.1 NZ_CP033076:3874768-3875190 [Buttiauxella sp. 3AFRM03]
VVLWQSDLRVSWRAQWLSLLVHGLVALFVLLMPWPMSYTLIWMLLLSLVVFDSVRSQRRIHACQGEMKLLTDYHLRWQNQ
EWEMVGAPWVLRSGMMLRLRRVGRKRSQHLWLSADSMDTGEWRDLRRLMLQQQASGNGEV

Download         Length: 423 bp

>T113064 NZ_CP033076:3874768-3875190 [Buttiauxella sp. 3AFRM03]
GTGGTCCTGTGGCAATCTGATCTTCGGGTCTCGTGGCGTGCACAATGGCTGTCCCTTTTGGTTCACGGTTTAGTGGCACT
CTTTGTGCTGCTGATGCCGTGGCCGATGAGCTACACGCTAATTTGGATGCTGTTGCTTTCGCTGGTGGTATTTGACAGCG
TTCGTAGCCAGCGCCGGATTCATGCTTGCCAGGGCGAAATGAAACTCCTGACCGACTACCACCTGCGGTGGCAAAACCAG
GAGTGGGAAATGGTTGGTGCGCCATGGGTATTACGCAGCGGCATGATGCTGCGTTTACGCCGCGTGGGGCGCAAGCGCAG
TCAACATTTATGGCTATCAGCCGACAGTATGGATACTGGCGAGTGGCGTGATTTACGCCGCCTGATGCTGCAACAACAGG
CAAGCGGGAATGGGGAAGTTTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10471.97 Da        Isoelectric Point: 5.1238

>AT113064 WP_064513590.1 NZ_CP033076:3874521-3874787 [Buttiauxella sp. 3AFRM03]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSTEDKQLFVRLLESDDPDLFNWLMNHGKPADTELQRMVTLIQTRN
KERGPVAI

Download         Length: 267 bp

>AT113064 NZ_CP033076:3874521-3874787 [Buttiauxella sp. 3AFRM03]
ATGGATATCAATAACAAAGCCCGAATTCATTGGGCGTGCCGCCGGGGAATGCGTGAGCTTGATATTTCGATTATGCCATT
CTTCGAATATGAATATGACTCGTTAAGCACTGAGGATAAGCAATTATTTGTCCGTTTGCTGGAAAGTGATGATCCTGACC
TGTTTAACTGGTTAATGAATCATGGCAAACCAGCAGATACAGAGCTGCAACGGATGGTGACACTGATTCAGACACGGAAT
AAAGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2IIE9

Antitoxin

Source ID Structure
AlphaFold DB A0A1B7I271

References