Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 2895104..2895635 Replicon chromosome
Accession NZ_CP033073
Organism Streptomyces sp. Z022

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D9753_RS12665 Protein ID WP_121787122.1
Coordinates 2895366..2895635 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D9753_RS12660 Protein ID WP_121787121.1
Coordinates 2895104..2895373 (+) Length 90 a.a.

Genomic Context

D9753_RS12645D9753_RS12660D9753_RS12665D9753_RS12670D9753_RS12675D9753_RS12685D9753_RS12690D9753_RS12695D9753_RS12700D9753_RS12705D9753_RS12640D9753_RS12650D9753_RS12655D9753_RS36525D9753_RS12680
Location: 2891751..2892929 (1179 bp)
Type: Others
Protein ID: WP_205614387.1
Location: 2895104..2895373 (270 bp)
Type: Antitoxin
Protein ID: WP_121787121.1
Location: 2895366..2895635 (270 bp)
Type: Toxin
Protein ID: WP_121787122.1
Location: 2895714..2895989 (276 bp)
Type: Others
Protein ID: WP_014048106.1
Location: 2895986..2896393 (408 bp)
Type: Others
Protein ID: WP_121787123.1
Location: 2897611..2898555 (945 bp)
Type: Others
Protein ID: Protein_2423
Location: 2898552..2898899 (348 bp)
Type: Others
Protein ID: WP_121787124.1
Location: 2898896..2899282 (387 bp)
Type: Others
Protein ID: WP_121787125.1
Location: 2899516..2899710 (195 bp)
Type: Others
Protein ID: Protein_2426
Location: 2899763..2900275 (513 bp)
Type: Others
Protein ID: WP_205614136.1
Location: 2890511..2891263 (753 bp)
Type: Others
Protein ID: WP_121787117.1
Location: 2893022..2894020 (999 bp)
Type: Others
Protein ID: WP_121787119.1
Location: 2894210..2894518 (309 bp)
Type: Others
Protein ID: WP_121787120.1
Location: 2894531..2894863 (333 bp)
Type: Others
Protein ID: WP_163010690.1
Location: 2896407..2897599 (1193 bp)
Type: Others
Protein ID: Protein_2422
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D9753_RS126402890511..2891263-753WP_121787117.1GntR family transcriptional regulator-
D9753_RS126452891751..2892929+1179WP_205614387.1proteinase inhibitor I4 serpin-
D9753_RS126502893022..2894020-999WP_121787119.12,3-diaminopropionate biosynthesis protein SbnB-
D9753_RS126552894210..2894518-309WP_121787120.1AzlD domain-containing protein-
D9753_RS365252894531..2894863-333WP_163010690.1hypothetical protein-
D9753_RS126602895104..2895373+270WP_121787121.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
D9753_RS126652895366..2895635+270WP_121787122.1type II toxin-antitoxin system RelE/ParE family toxinToxin
D9753_RS126702895714..2895989+276WP_014048106.1hypothetical protein-
D9753_RS126752895986..2896393+408WP_121787123.1PIN domain-containing protein-
D9753_RS126802896407..2897599-1193Protein_2422type I restriction endonuclease subunit R-
D9753_RS126852897611..2898555+945Protein_2423hypothetical protein-
D9753_RS126902898552..2898899+348WP_121787124.1hypothetical protein-
D9753_RS126952898896..2899282+387WP_121787125.1hypothetical protein-
D9753_RS127002899516..2899710+195Protein_2426hypothetical protein-
D9753_RS127052899763..2900275+513WP_205614136.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-79)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-58)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10281.86 Da        Isoelectric Point: 10.3620

>T113044 WP_121787122.1 NZ_CP033073:2895366-2895635 [Streptomyces sp. Z022]
VSEYRTVFRPEAQAELRKIRRDMALRILAKLTELESDPLGFNTTALVSQPERRRLRGGDYRVVYTIDNGELVVWVVHVST
GFSAKYKKI

Download         Length: 270 bp

>T113044 NZ_CP033073:2895366-2895635 [Streptomyces sp. Z022]
GTGAGTGAGTACCGAACCGTCTTCCGACCGGAGGCGCAGGCCGAGCTCCGGAAGATCCGTCGCGACATGGCCTTGCGCAT
CCTGGCCAAACTGACCGAGCTGGAGAGCGACCCCCTCGGCTTCAACACCACCGCGCTCGTGTCACAGCCAGAACGCCGTC
GACTGCGGGGCGGCGACTACCGGGTCGTCTACACGATCGACAACGGAGAGCTCGTGGTGTGGGTCGTCCACGTCAGCACG
GGATTCTCGGCAAAGTACAAGAAGATCTAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10286.78 Da        Isoelectric Point: 4.7473

>AT113044 WP_121787121.1 NZ_CP033073:2895104-2895373 [Streptomyces sp. Z022]
MTQPLPIESIRDVRAHLAEVVERADRDDVPTVITRRGKQVAAVVSIEVLRKYQEWEEREINRIIDERMANPVPGIPIEDI
MRETLARGE

Download         Length: 270 bp

>AT113044 NZ_CP033073:2895104-2895373 [Streptomyces sp. Z022]
ATGACGCAGCCCCTACCCATAGAGTCCATCCGCGACGTACGCGCGCACCTAGCCGAGGTCGTGGAGCGCGCCGATCGAGA
CGACGTGCCCACCGTGATCACCCGACGGGGCAAGCAGGTCGCCGCCGTCGTCTCCATCGAGGTGCTGCGCAAGTACCAGG
AGTGGGAAGAGCGCGAGATCAACCGGATCATCGACGAGCGCATGGCCAACCCTGTACCCGGCATCCCGATCGAGGACATC
ATGAGGGAGACGCTGGCGCGCGGTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References