Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3099682..3100494 Replicon chromosome
Accession NZ_CP033055
Organism Serratia sp. 3ACOL1

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag D9980_RS13960 Protein ID WP_121607611.1
Coordinates 3100111..3100494 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag D9980_RS13955 Protein ID WP_121607610.1
Coordinates 3099682..3100050 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D9980_RS13915 3094794..3095669 + 876 WP_121607606.1 GTPase family protein -
D9980_RS13920 3095882..3096583 + 702 WP_121607607.1 WYL domain-containing protein -
D9980_RS13925 3096589..3097236 + 648 WP_121607608.1 hypothetical protein -
D9980_RS13935 3097610..3098077 + 468 WP_172668986.1 hypothetical protein -
D9980_RS13940 3098313..3098759 + 447 WP_121607609.1 antirestriction protein -
D9980_RS13945 3098779..3099258 + 480 WP_115115199.1 DNA repair protein RadC -
D9980_RS13950 3099269..3099589 + 321 Protein_2731 hypothetical protein -
D9980_RS13955 3099682..3100050 + 369 WP_121607610.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
D9980_RS13960 3100111..3100494 + 384 WP_121607611.1 TA system toxin CbtA family protein Toxin
D9980_RS13965 3100491..3100712 + 222 WP_121607612.1 hypothetical protein -
D9980_RS13970 3100807..3101658 + 852 WP_121607613.1 DUF4942 domain-containing protein -
D9980_RS13975 3102371..3102637 + 267 WP_121607614.1 DUF1778 domain-containing protein -
D9980_RS13980 3102641..3103156 + 516 WP_121607615.1 GNAT family N-acetyltransferase -
D9980_RS13985 3103269..3103526 + 258 WP_121607616.1 hypothetical protein -
D9980_RS13990 3103579..3103926 - 348 WP_121607617.1 hypothetical protein -
D9980_RS13995 3104141..3104779 + 639 WP_121607618.1 LysE family transporter -
D9980_RS14000 3104901..3105203 + 303 WP_024485301.1 metalloregulator ArsR/SmtB family transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-111)

Antitoxin

Antitoxin CbeA

(18-117)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14314.53 Da        Isoelectric Point: 9.9985

>T113011 WP_121607611.1 NZ_CP033055:3100111-3100494 [Serratia sp. 3ACOL1]
MQTVLVTPKRAAQSCPSPIAIWQVLMTHLLQQHYGLTLEDTAFSHEGVIQEHLNAGISLADALNFIVEKYELVRIDRTGF
SIREQSPFITPIDILRARQATGLMKRRGYKAITHITNGKNQRQGVHP

Download         Length: 384 bp

>T113011 NZ_CP033055:3100111-3100494 [Serratia sp. 3ACOL1]
ATGCAAACTGTATTGGTTACCCCGAAACGGGCGGCACAGTCTTGCCCATCACCCATCGCGATCTGGCAGGTATTGATGAC
CCATCTATTGCAACAACACTATGGTCTGACACTGGAAGATACCGCCTTTAGTCACGAGGGTGTGATCCAAGAGCATCTTA
ATGCAGGGATTTCCCTGGCGGATGCGCTGAATTTTATCGTGGAAAAATATGAACTGGTCCGTATTGATCGCACCGGTTTT
AGTATCCGTGAACAATCACCGTTTATTACGCCTATCGATATTCTCCGGGCCCGACAGGCTACTGGTCTGATGAAACGCCG
AGGTTACAAGGCCATCACTCATATCACCAACGGTAAAAACCAACGACAGGGGGTACATCCGTGA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13549.39 Da        Isoelectric Point: 6.3171

>AT113011 WP_121607610.1 NZ_CP033055:3099682-3100050 [Serratia sp. 3ACOL1]
MTDSKPDTPSQRADITPPAWGLKRIITPQFGARLVQQGHQLHYLADRADIVGKFSDAELRHLDQVFPLWLQQLESMLMSA
ELNPRQQHCVTLHASGLTLEADTLGSCGYVYISIYPTSATTA

Download         Length: 369 bp

>AT113011 NZ_CP033055:3099682-3100050 [Serratia sp. 3ACOL1]
ATGACCGATAGTAAACCTGATACCCCCTCCCAGCGGGCTGATATCACCCCACCAGCCTGGGGACTAAAACGTATCATCAC
ACCACAGTTTGGTGCTCGCCTGGTACAGCAAGGCCACCAACTGCATTACCTGGCAGACCGTGCCGATATCGTGGGGAAGT
TCAGTGATGCCGAGTTGCGTCATCTCGACCAGGTATTCCCGCTATGGCTTCAGCAGTTGGAGTCGATGCTGATGTCTGCT
GAACTCAATCCCCGACAACAACACTGCGTCACACTCCATGCGAGCGGACTGACACTCGAAGCCGATACGTTGGGCTCCTG
CGGGTACGTGTATATATCTATCTATCCAACATCAGCTACAACTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References