Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | spoIISABC/SpoIISA-SpoIISB |
| Location | 1517720..1518636 | Replicon | chromosome |
| Accession | NZ_CP033052 | ||
| Organism | Bacillus vallismortis strain Bac111 | ||
Toxin (Protein)
| Gene name | spoIISA | Uniprot ID | - |
| Locus tag | D9779_RS07860 | Protein ID | WP_121642402.1 |
| Coordinates | 1517890..1518636 (-) | Length | 249 a.a. |
Antitoxin (Protein)
| Gene name | spoIISB | Uniprot ID | A0A5D4N4Z5 |
| Locus tag | D9779_RS07855 | Protein ID | WP_010330434.1 |
| Coordinates | 1517720..1517890 (-) | Length | 57 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| D9779_RS07820 | 1514327..1514656 | + | 330 | WP_121642398.1 | XkdW family protein | - |
| D9779_RS07825 | 1514653..1514817 | + | 165 | WP_010330429.1 | XkdX family protein | - |
| D9779_RS07830 | 1514861..1515700 | + | 840 | WP_121642399.1 | phage portal protein | - |
| D9779_RS07835 | 1515753..1516022 | + | 270 | WP_010330431.1 | hemolysin XhlA family protein | - |
| D9779_RS07840 | 1516038..1516301 | + | 264 | WP_010330432.1 | phage holin | - |
| D9779_RS07845 | 1516314..1517207 | + | 894 | WP_121642400.1 | N-acetylmuramoyl-L-alanine amidase | - |
| D9779_RS07850 | 1517498..1517635 | - | 138 | WP_121642401.1 | three component toxin-antitoxin-antitoxin system antitoxin SpoIISC | - |
| D9779_RS07855 | 1517720..1517890 | - | 171 | WP_010330434.1 | three component toxin-antitoxin-antitoxin system antitoxin SpoIISB | Antitoxin |
| D9779_RS07860 | 1517890..1518636 | - | 747 | WP_121642402.1 | type II toxin-antitoxin system SpoIISA family toxin | Toxin |
| D9779_RS07865 | 1518746..1519747 | - | 1002 | WP_010330436.1 | inorganic phosphate transporter family protein | - |
| D9779_RS07870 | 1519760..1520377 | - | 618 | WP_003218470.1 | DUF47 domain-containing protein | - |
| D9779_RS07875 | 1520653..1521969 | - | 1317 | WP_010330437.1 | serine/threonine exchanger | - |
| D9779_RS07880 | 1522354..1523304 | + | 951 | WP_121642403.1 | ring-cleaving dioxygenase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 28965.49 Da Isoelectric Point: 4.6089
>T112997 WP_121642402.1 NZ_CP033052:c1518636-1517890 [Bacillus vallismortis]
MLLFFQIMVWCIMAGLGLYVYATWRFEAKVKEKMPAIRKTWYLLFVLGAMIYWTYKPSSLFDDWGRYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLDRLKTYQCLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNVTASL
CHYSTQTDKDRLTEHMDNPADVQTRLDRKDVYYDQYGKVVLIPFTIETQSYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG
MLLFFQIMVWCIMAGLGLYVYATWRFEAKVKEKMPAIRKTWYLLFVLGAMIYWTYKPSSLFDDWGRYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLDRLKTYQCLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNVTASL
CHYSTQTDKDRLTEHMDNPADVQTRLDRKDVYYDQYGKVVLIPFTIETQSYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG
Download Length: 747 bp
>T112997 NZ_CP033052:c1518636-1517890 [Bacillus vallismortis]
ATGCTTTTATTCTTTCAGATCATGGTCTGGTGCATCATGGCCGGATTAGGCTTGTACGTGTACGCCACGTGGCGTTTCGA
AGCGAAAGTCAAAGAAAAAATGCCCGCCATCCGGAAAACATGGTACTTGCTGTTTGTTTTGGGCGCTATGATATACTGGA
CATATAAGCCCTCTTCCCTGTTTGACGACTGGGGACGGTATCTCATTGTCGCCGTCAGTTTCGCTTTAATTGACGCTTTC
ATCTTCTTAAGTGCGTACGTCAAAAAACTGGCCGGCAGCGAACTGGAAACAGACACAAGAGAAATCCTCGAAGAAAACAA
CGAAATGCTTCACATGTATCTCGATCGGCTGAAAACATACCAATGCCTATTGAAAAACGAACCGATCCACGTTTATTATG
GAAGTATAGATGCATATGCTGAAGGTATTGATAAGCTGCTGAAAACCTATGCAGATAAAATGAATGTAACGGCCTCCCTC
TGTCACTATTCAACACAGACCGACAAGGACCGATTAACTGAGCATATGGACAATCCCGCGGACGTGCAAACACGGCTCGA
TCGAAAAGATGTGTATTACGACCAATACGGAAAAGTGGTTCTCATCCCTTTTACCATCGAGACACAAAGCTACGTCATCA
AGCTGACGTCTGACAGCATTGTCACGGAATTTGATTATTTGCTTTTCACATCATTAACGAGCATATATGATTTGGTGCTG
CCAATTGAGGAGGAAGGTGAAGGATAA
ATGCTTTTATTCTTTCAGATCATGGTCTGGTGCATCATGGCCGGATTAGGCTTGTACGTGTACGCCACGTGGCGTTTCGA
AGCGAAAGTCAAAGAAAAAATGCCCGCCATCCGGAAAACATGGTACTTGCTGTTTGTTTTGGGCGCTATGATATACTGGA
CATATAAGCCCTCTTCCCTGTTTGACGACTGGGGACGGTATCTCATTGTCGCCGTCAGTTTCGCTTTAATTGACGCTTTC
ATCTTCTTAAGTGCGTACGTCAAAAAACTGGCCGGCAGCGAACTGGAAACAGACACAAGAGAAATCCTCGAAGAAAACAA
CGAAATGCTTCACATGTATCTCGATCGGCTGAAAACATACCAATGCCTATTGAAAAACGAACCGATCCACGTTTATTATG
GAAGTATAGATGCATATGCTGAAGGTATTGATAAGCTGCTGAAAACCTATGCAGATAAAATGAATGTAACGGCCTCCCTC
TGTCACTATTCAACACAGACCGACAAGGACCGATTAACTGAGCATATGGACAATCCCGCGGACGTGCAAACACGGCTCGA
TCGAAAAGATGTGTATTACGACCAATACGGAAAAGTGGTTCTCATCCCTTTTACCATCGAGACACAAAGCTACGTCATCA
AGCTGACGTCTGACAGCATTGTCACGGAATTTGATTATTTGCTTTTCACATCATTAACGAGCATATATGATTTGGTGCTG
CCAATTGAGGAGGAAGGTGAAGGATAA
Antitoxin
Download Length: 57 a.a. Molecular weight: 6495.49 Da Isoelectric Point: 10.8401
>AT112997 WP_010330434.1 NZ_CP033052:c1517890-1517720 [Bacillus vallismortis]
MERAFQNGCEPRAAKPSKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA
MERAFQNGCEPRAAKPSKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA
Download Length: 171 bp
>AT112997 NZ_CP033052:c1517890-1517720 [Bacillus vallismortis]
ATGGAACGCGCGTTTCAAAACGGGTGCGAGCCCAGAGCGGCAAAACCGTCAAAGATCCTGAAAAAACGTTCAACCACCAG
TGTCGCAAGCTATCAAGTCAGCCCGCATACAGCAAGAATCTTCAAAGAAAACGAACGGCTGATTGACGAGTATAAACGAA
AAAAAGCATGA
ATGGAACGCGCGTTTCAAAACGGGTGCGAGCCCAGAGCGGCAAAACCGTCAAAGATCCTGAAAAAACGTTCAACCACCAG
TGTCGCAAGCTATCAAGTCAGCCCGCATACAGCAAGAATCTTCAAAGAAAACGAACGGCTGATTGACGAGTATAAACGAA
AAAAAGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|