Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhRel2-ATphRel2/DUF4065(antitoxin)
Location 938036..939504 Replicon chromosome
Accession NZ_CP033048
Organism Virgibacillus sp. Bac330

Toxin (Protein)


Gene name phRel2 Uniprot ID -
Locus tag D9780_RS04195 Protein ID WP_162985784.1
Coordinates 938036..938740 (+) Length 235 a.a.

Antitoxin (Protein)


Gene name ATphRel2 Uniprot ID -
Locus tag D9780_RS04200 Protein ID WP_121639391.1
Coordinates 938755..939504 (+) Length 250 a.a.

Genomic Context

D9780_RS04175D9780_RS20965D9780_RS20970D9780_RS04185D9780_RS04190D9780_RS04195D9780_RS04200D9780_RS04210D9780_RS04215D9780_RS04220D9780_RS04225D9780_RS04230D9780_RS04205
Location: 933083..933364 (282 bp)
Type: Others
Protein ID: WP_121639388.1
Location: 934147..934449 (303 bp)
Type: Others
Protein ID: Protein_816
Location: 935870..936007 (138 bp)
Type: Others
Protein ID: WP_162985783.1
Location: 936094..936525 (432 bp)
Type: Others
Protein ID: WP_121641425.1
Location: 936582..937658 (1077 bp)
Type: Others
Protein ID: WP_121639389.1
Location: 938036..938740 (705 bp)
Type: Toxin
Protein ID: WP_162985784.1
Location: 938755..939504 (750 bp)
Type: Antitoxin
Protein ID: WP_121639391.1
Location: 939852..940067 (216 bp)
Type: Others
Protein ID: WP_121639393.1
Location: 940067..940381 (315 bp)
Type: Others
Protein ID: WP_121639394.1
Location: 941835..942290 (456 bp)
Type: Others
Protein ID: WP_121641426.1
Location: 942305..942754 (450 bp)
Type: Others
Protein ID: WP_121639395.1
Location: 943668..944117 (450 bp)
Type: Others
Protein ID: WP_205601130.1
Location: 939532..939717 (186 bp)
Type: Others
Protein ID: WP_121639392.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
D9780_RS04175933083..933364+282WP_121639388.1ketopantoate hydroxymethyltransferase-
D9780_RS20965934147..934449+303Protein_816phage baseplate upper protein-
D9780_RS20970935870..936007+138WP_162985783.1hypothetical protein-
D9780_RS04185936094..936525+432WP_121641425.1phage holin family protein-
D9780_RS04190936582..937658+1077WP_121639389.1N-acetylmuramoyl-L-alanine amidase-
D9780_RS04195938036..938740+705WP_162985784.1hypothetical proteinToxin
D9780_RS04200938755..939504+750WP_121639391.1DUF4065 domain-containing proteinAntitoxin
D9780_RS04205939532..939717-186WP_121639392.1hypothetical protein-
D9780_RS04210939852..940067+216WP_121639393.1hypothetical protein-
D9780_RS04215940067..940381+315WP_121639394.1YolD-like family protein-
D9780_RS04220941835..942290+456WP_121641426.1HNH/ENDO VII family nuclease-
D9780_RS04225942305..942754+450WP_121639395.1SMI1/KNR4 family protein-
D9780_RS04230943668..944117+450WP_205601130.1MepB family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--889610..94038150771


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(113-225)


Sequences

Toxin        


Download         Length: 235 a.a.        Molecular weight: 27872.06 Da        Isoelectric Point: 7.9753

>T112992 WP_162985784.1 NZ_CP033048:938036-938740 [Virgibacillus sp. Bac330]
MNTAKDKIIANNSIVEYDIEIIEEIIHEIINLHQKFSYMYGNLCSLNLKRNKIRDVVSIMDNNSYLINNNFLSIVYNYLE
ELKMLIVDIDLEERYKHLDFRPRTKDPESVFYKIGHYFAKAGKGTYSINKCLNDLLGFRICIKNFDHKCSIFYTLCDYIK
EEDYNIKCIDSSKGDYKATHIYIKGPSNKFFPWELQVWNLDDREVNYESHKMHKQMYKKSAEIHKNGFTIVKRP

Download         Length: 705 bp

>T112992 NZ_CP033048:938036-938740 [Virgibacillus sp. Bac330]
ATGAATACTGCTAAAGATAAAATAATAGCAAATAACAGCATTGTTGAATATGATATCGAGATAATCGAAGAGATAATTCA
TGAAATAATAAATCTACACCAGAAATTTTCATATATGTATGGGAATCTGTGTAGTTTAAACCTTAAACGAAATAAGATAA
GGGATGTAGTTAGCATAATGGATAACAATAGTTATCTTATAAACAATAACTTCCTTTCAATTGTCTATAATTATTTAGAA
GAGCTAAAAATGTTAATAGTAGATATAGACTTAGAGGAAAGATACAAACATTTGGATTTTAGACCGAGAACAAAAGATCC
TGAAAGTGTTTTTTATAAAATAGGGCATTATTTTGCGAAAGCTGGAAAAGGTACCTATTCAATTAATAAATGTCTAAATG
ATTTACTTGGGTTTCGAATATGTATAAAAAACTTTGACCATAAGTGCAGTATATTTTATACTTTATGTGACTATATTAAA
GAAGAGGATTATAATATAAAATGTATAGACTCATCAAAAGGTGATTATAAAGCTACACACATATATATTAAAGGGCCAAG
TAATAAGTTCTTTCCATGGGAACTGCAAGTATGGAATTTAGACGATAGAGAAGTAAATTATGAATCACATAAAATGCATA
AACAGATGTATAAAAAGTCTGCTGAAATACATAAAAATGGATTTACAATAGTTAAACGACCTTGA

Antitoxin


Download         Length: 250 a.a.        Molecular weight: 28724.89 Da        Isoelectric Point: 6.3003

>AT112992 WP_121639391.1 NZ_CP033048:938755-939504 [Virgibacillus sp. Bac330]
MAYHFLAITSSYSKGYRIGWNYSSEDTLDKAVIKRFLTKMKKRCGDVQFGIHKITTNSLSISSVKEKDMFFEDVVFTSDM
DQFISLVASDQKLSALDISKFVLTMLPMSHIKLQKILYYTYAEFLKRTGEKLFKEPIVSYKYGPVVESVFREFTEHGALI
IDYEEDENFVIVADDVATTPSFIKVISSEHGSTVIDCVMDTLQRYGDEKPFNLVDKTHRVGGPWQRVYEPSQNNIITDDL
ILQYHHFVK

Download         Length: 750 bp

>AT112992 NZ_CP033048:938755-939504 [Virgibacillus sp. Bac330]
ATGGCTTATCACTTTTTAGCGATAACAAGCTCGTACTCTAAAGGCTATAGAATTGGTTGGAATTATTCTTCTGAGGATAC
ATTAGATAAGGCAGTGATTAAAAGATTTTTAACAAAGATGAAAAAAAGATGCGGGGATGTTCAATTCGGCATCCATAAAA
TTACTACTAATTCTTTATCCATTTCCTCAGTTAAAGAAAAGGATATGTTCTTTGAGGACGTTGTTTTTACCAGTGATATG
GATCAGTTCATTTCCCTTGTAGCGAGTGATCAGAAATTATCAGCTCTAGATATTTCCAAATTTGTTTTAACTATGTTGCC
AATGTCACACATAAAATTACAAAAGATTCTATATTACACGTATGCAGAATTCCTAAAAAGAACCGGGGAAAAATTATTTA
AAGAACCAATCGTTTCTTATAAATATGGACCGGTTGTAGAGAGCGTTTTTAGAGAGTTCACTGAGCACGGTGCATTAATT
ATTGATTACGAAGAAGATGAAAACTTTGTAATAGTCGCTGATGATGTAGCAACTACACCTTCATTCATCAAGGTTATTTC
CTCAGAGCATGGTTCAACTGTGATTGATTGTGTAATGGATACTTTACAGAGATATGGTGATGAAAAACCATTTAATTTAG
TTGATAAAACTCACAGGGTAGGTGGTCCTTGGCAAAGGGTTTATGAACCAAGCCAAAACAACATAATTACTGATGATCTT
ATATTACAATATCATCATTTTGTAAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References