Detailed information of TA system TA112981

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 202896..203566
• Replicon: plasmid pAtA6
• Accession: NZ_CP033029
• Organism: Agrobacterium tumefaciens strain A6

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: AtA6_RS24710
• Protein ID: WP_003517201.1
• Coordinates: 203147..203566 (+)
• Length: 140 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A7U5CZ71
• Locus tag: AtA6_RS24705
• Protein ID: WP_038496682.1
• Coordinates: 202896..203150 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AtA6_RS24695	200647..201866	+	1220	WP_121556223.1	IS3 family transposase	-
AtA6_RS24700	201923..202528	-	606	WP_035201472.1	J domain-containing protein	-
AtA6_RS24705	202896..203150	+	255	WP_038496682.1	plasmid stabilization protein	Antitoxin
AtA6_RS24710	203147..203566	+	420	WP_003517201.1	type II toxin-antitoxin system VapC family toxin	Toxin
AtA6_RS24715	203793..204689	-	897	WP_038496685.1	dihydrodipicolinate synthase family protein	-
AtA6_RS24720	204722..205603	-	882	WP_038496688.1	SMP-30/gluconolactonase/LRE family protein	-
AtA6_RS24725	205660..206379	-	720	WP_038496691.1	FadR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..815853	815853

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Ribbon-helix-helix protein, CopG (6-41)

Sequences

Toxin

Protein

• Length: 140 a.a.
• Molecular weight: 17962.39 Da
• Isoelectric Point: 12.9430

>T112981 WP_003517201.1 NZ_CP033029:203147-203566 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 420 bp

>T112981 NZ_CP033029:203147-203566 [Agrobacterium tumefaciens]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 10912.81 Da
• Isoelectric Point: 12.7242

>AT112981 WP_038496682.1 NZ_CP033029:202896-203150 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKK

Nucleotide

• Length: 255 bp

>AT112981 NZ_CP033029:202896-203150 [Agrobacterium tumefaciens]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAA

Structures

Antitoxin

• AlphaFold DB: A0A7U5CZ71