Detailed information of TA system TA112980

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/CC2985(antitoxin)
• Location: 120853..121400
• Replicon: plasmid pAtA6
• Accession: NZ_CP033029
• Organism: Agrobacterium tumefaciens strain A6

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: AtA6_RS24285
• Protein ID: WP_038496495.1
• Coordinates: 121107..121400 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: A0A7U5CZ68
• Locus tag: AtA6_RS24280
• Protein ID: WP_003519100.1
• Coordinates: 120853..121107 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AtA6_RS24265	116366..118126	+	1761	WP_038496489.1	penicillin-binding protein 2	-
AtA6_RS24270	118120..118740	-	621	WP_075807885.1	TetR/AcrR family transcriptional regulator	-
AtA6_RS24275	119352..120517	-	1166	Protein_121	IS110 family transposase	-
AtA6_RS24280	120853..121107	+	255	WP_003519100.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
AtA6_RS24285	121107..121400	+	294	WP_038496495.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AtA6_RS24295	121822..123191	+	1370	Protein_124	transposase	-
AtA6_RS24300	123545..124444	+	900	WP_046205651.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..815853	815853

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-122)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 12579.08 Da
• Isoelectric Point: 12.7867

>T112980 WP_038496495.1 NZ_CP033029:121107-121400 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 294 bp

>T112980 NZ_CP033029:121107-121400 [Agrobacterium tumefaciens]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 10912.81 Da
• Isoelectric Point: 12.7242

>AT112980 WP_003519100.1 NZ_CP033029:120853-121107 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKK

Nucleotide

• Length: 255 bp

>AT112980 NZ_CP033029:120853-121107 [Agrobacterium tumefaciens]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAA

Structures

Antitoxin

• AlphaFold DB: A0A7U5CZ68