Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 1483811..1484339 Replicon chromosome
Accession NZ_CP033019
Organism Janthinobacterium agaricidamnosum strain BHSEK

Toxin (Protein)


Gene name parE Uniprot ID A0A2G3MAU3
Locus tag D9M09_RS06810 Protein ID WP_070291352.1
Coordinates 1483811..1484101 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A853STY9
Locus tag D9M09_RS06815 Protein ID WP_070224900.1
Coordinates 1484094..1484339 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D9M09_RS06785 1479704..1480816 + 1113 WP_099409913.1 AI-2E family transporter -
D9M09_RS06790 1480924..1481148 - 225 WP_010396348.1 hypothetical protein -
D9M09_RS06795 1481313..1482047 + 735 WP_121670991.1 phosphatase PAP2 family protein -
D9M09_RS06800 1482059..1482967 + 909 WP_121670990.1 diacylglycerol kinase family lipid kinase -
D9M09_RS06805 1482977..1483795 + 819 WP_070224898.1 metallophosphoesterase -
D9M09_RS06810 1483811..1484101 - 291 WP_070291352.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
D9M09_RS06815 1484094..1484339 - 246 WP_070224900.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
D9M09_RS06820 1484436..1485827 - 1392 WP_121668902.1 cardiolipin synthase -
D9M09_RS06825 1485824..1487935 - 2112 WP_070225020.1 site-specific recombinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(7-76)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11243.84 Da        Isoelectric Point: 8.8795

>T112950 WP_070291352.1 NZ_CP033019:c1484101-1483811 [Janthinobacterium agaricidamnosum]
MAEYRLTPAAEHDLEAIWAYTSQRWNVQQASLYLDNMTAAFDDLARAPETAPACEQIRPGYRRRKVGRHMIYFRITHYGI
AIVRILHDRMDAARHL

Download         Length: 291 bp

>T112950 NZ_CP033019:c1484101-1483811 [Janthinobacterium agaricidamnosum]
ATGGCTGAATACCGGCTGACGCCCGCCGCCGAGCATGATCTTGAGGCGATCTGGGCGTATACGTCGCAGCGCTGGAACGT
GCAGCAGGCCAGTCTTTATCTTGACAACATGACGGCGGCCTTCGATGACCTGGCACGCGCACCCGAGACGGCACCGGCAT
GCGAGCAGATTCGGCCCGGCTACCGGCGCCGCAAAGTGGGACGGCACATGATTTATTTCCGCATCACTCACTATGGCATT
GCCATCGTCCGCATTTTGCATGACCGCATGGATGCGGCACGCCATCTGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9193.21 Da        Isoelectric Point: 4.8232

>AT112950 WP_070224900.1 NZ_CP033019:c1484339-1484094 [Janthinobacterium agaricidamnosum]
MGTVRKTITLTDQQDDWIKAQIDAGRYTNDSEYIRDLIRREQERSAELDAIRAALVEGEASGEPQPFDARAFKQRMLAAH
G

Download         Length: 246 bp

>AT112950 NZ_CP033019:c1484339-1484094 [Janthinobacterium agaricidamnosum]
ATGGGAACCGTGCGCAAGACCATTACCTTGACGGACCAGCAGGACGACTGGATCAAGGCGCAAATTGACGCCGGGCGCTA
TACGAACGACAGCGAATACATCCGCGACCTGATCCGGCGTGAACAGGAACGCAGCGCCGAACTCGATGCGATCCGCGCGG
CGCTGGTGGAAGGCGAGGCCAGCGGTGAACCCCAGCCTTTCGACGCCAGGGCTTTCAAGCAGAGAATGCTGGCAGCGCAT
GGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G3MAU3

Antitoxin

Source ID Structure
AlphaFold DB A0A853STY9

References