Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2199395..2199666 Replicon chromosome
Accession NZ_CP032989
Organism Escherichia coli strain W2-5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2199525..2199628 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2199395..2199666 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D9V55_RS11085 2195949..2196611 - 663 WP_000944256.1 exodeoxyribonuclease X -
D9V55_RS11090 2196635..2197292 - 658 Protein_2071 carbon-nitrogen hydrolase family protein -
D9V55_RS11095 2197394..2197624 - 231 WP_000916763.1 DNA polymerase III subunit theta -
D9V55_RS11100 2197763..2198137 + 375 WP_000204699.1 CopC domain-containing protein YobA -
D9V55_RS11105 2198141..2199013 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
D9V55_RS11110 2199026..2199367 + 342 WP_000976492.1 YebY family protein -
- 2199395..2199666 - 272 - - Antitoxin
- 2199525..2199628 + 104 - - Toxin
D9V55_RS11115 2199763..2200419 + 657 WP_024258105.1 protein-serine/threonine phosphatase -
D9V55_RS11120 2200420..2200611 - 192 WP_001296140.1 YebW family protein -
D9V55_RS11125 2200716..2200952 - 237 WP_001295499.1 DUF1480 family protein -
D9V55_RS11130 2201070..2202509 - 1440 WP_001512833.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T112895 NZ_CP032989:2199525-2199628 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT112895 NZ_CP032989:c2199666-2199395 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGTAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References