Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 480182..480762 Replicon plasmid pAt1D1460
Accession NZ_CP032928
Organism Agrobacterium tumefaciens strain 1D1460

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag At1D1460_RS26885 Protein ID WP_121593637.1
Coordinates 480379..480762 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag At1D1460_RS26880 Protein ID WP_080868762.1
Coordinates 480182..480382 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
At1D1460_RS26865 476003..476644 + 642 WP_162993132.1 helix-turn-helix domain-containing protein -
At1D1460_RS26870 476743..478941 - 2199 WP_121593635.1 EAL domain-containing protein -
At1D1460_RS26875 479664..479990 - 327 WP_121593636.1 transposase -
At1D1460_RS26880 480182..480382 + 201 WP_080868762.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
At1D1460_RS26885 480379..480762 + 384 WP_121593637.1 type II toxin-antitoxin system VapC family toxin Toxin
At1D1460_RS26890 481102..481307 - 206 Protein_494 aldo/keto reductase -
At1D1460_RS26900 481669..482007 + 339 Protein_495 helix-turn-helix transcriptional regulator -
At1D1460_RS28470 482125..482448 + 324 WP_162993137.1 hypothetical protein -
At1D1460_RS26910 482556..483407 - 852 WP_121593638.1 2-hydroxy-3-oxopropionate reductase -
At1D1460_RS26915 483411..484196 - 786 WP_060724635.1 hydroxypyruvate isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..520191 520191


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-54)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 16424.30 Da        Isoelectric Point: 12.9037

>T112863 WP_121593637.1 NZ_CP032928:480379-480762 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 384 bp

>T112863 NZ_CP032928:480379-480762 [Agrobacterium tumefaciens]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 8605.68 Da        Isoelectric Point: 12.6195

>AT112863 WP_080868762.1 NZ_CP032928:480182-480382 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 201 bp

>AT112863 NZ_CP032928:480182-480382 [Agrobacterium tumefaciens]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References