Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 275620..276410 Replicon plasmid pAt1D1108a
Accession NZ_CP032923
Organism Agrobacterium tumefaciens strain 1D1108

Toxin (Protein)


Gene name TacT2 Uniprot ID A0A1S7NFF1
Locus tag At1D1108_RS25020 Protein ID WP_019565755.1
Coordinates 275913..276410 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID A0A1S7NER6
Locus tag At1D1108_RS25015 Protein ID WP_019565754.1
Coordinates 275620..275916 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
At1D1108_RS24995 270988..272712 + 1725 WP_019565751.1 ABC transporter ATP-binding protein -
At1D1108_RS25000 272757..273944 + 1188 WP_013637437.1 galactarate dehydratase -
At1D1108_RS25005 273931..274797 + 867 WP_113292295.1 aldose 1-epimerase -
At1D1108_RS25015 275620..275916 + 297 WP_019565754.1 DUF1778 domain-containing protein Antitoxin
At1D1108_RS25020 275913..276410 + 498 WP_019565755.1 GNAT family N-acetyltransferase Toxin
At1D1108_RS25025 277029..277577 + 549 WP_080802828.1 TRAP transporter small permease subunit -
At1D1108_RS25030 277595..279100 + 1506 WP_019565758.1 TRAP transporter large permease subunit -
At1D1108_RS25035 279164..280276 + 1113 WP_065703185.1 TRAP transporter substrate-binding protein -
At1D1108_RS25040 280340..280972 - 633 WP_121557717.1 response regulator transcription factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..502274 502274


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 21294.92 Da        Isoelectric Point: 13.0174

>T112860 WP_019565755.1 NZ_CP032923:275913-276410 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKK

Download         Length: 498 bp

>T112860 NZ_CP032923:275913-276410 [Agrobacterium tumefaciens]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 12707.25 Da        Isoelectric Point: 12.7912

>AT112860 WP_019565754.1 NZ_CP032923:275620-275916 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKK

Download         Length: 297 bp

>AT112860 NZ_CP032923:275620-275916 [Agrobacterium tumefaciens]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1S7NFF1

Antitoxin

Source ID Structure
AlphaFold DB A0A1S7NER6

References