Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 263093..263763 Replicon plasmid pAt1D1108a
Accession NZ_CP032923
Organism Agrobacterium tumefaciens strain 1D1108

Toxin (Protein)


Gene name vapC Uniprot ID A0A1S7NEN4
Locus tag At1D1108_RS24960 Protein ID WP_025591525.1
Coordinates 263344..263763 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID F0LGD9
Locus tag At1D1108_RS24955 Protein ID WP_003517203.1
Coordinates 263093..263347 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
At1D1108_RS24920 258125..258913 + 789 WP_025591510.1 ABC transporter permease -
At1D1108_RS24925 258915..260423 + 1509 WP_121557713.1 carboxylesterase family protein -
At1D1108_RS24930 260472..261419 + 948 WP_080802808.1 LysR family transcriptional regulator -
At1D1108_RS28050 261576..261884 + 309 WP_162995320.1 hypothetical protein -
At1D1108_RS24940 262123..262329 - 207 WP_025591519.1 hypothetical protein -
At1D1108_RS24955 263093..263347 + 255 WP_003517203.1 plasmid stabilization protein Antitoxin
At1D1108_RS24960 263344..263763 + 420 WP_025591525.1 type II toxin-antitoxin system VapC family toxin Toxin
At1D1108_RS24965 263903..264799 - 897 WP_013637432.1 dihydrodipicolinate synthase family protein -
At1D1108_RS24970 264832..265713 - 882 WP_121557715.1 SMP-30/gluconolactonase/LRE family protein -
At1D1108_RS24975 265770..266489 - 720 WP_003517195.1 FadR family transcriptional regulator -
At1D1108_RS24980 266789..268738 + 1950 WP_121557716.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..502274 502274


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-103)

Antitoxin

HigA2-like, helix-turn-helix domain

(35-98)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 17962.39 Da        Isoelectric Point: 12.9430

>T112859 WP_025591525.1 NZ_CP032923:263344-263763 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 420 bp

>T112859 NZ_CP032923:263344-263763 [Agrobacterium tumefaciens]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 10912.81 Da        Isoelectric Point: 12.7242

>AT112859 WP_003517203.1 NZ_CP032923:263093-263347 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKK

Download         Length: 255 bp

>AT112859 NZ_CP032923:263093-263347 [Agrobacterium tumefaciens]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1S7NEN4

Antitoxin

Source ID Structure
AlphaFold DB F0LGD9

References