Detailed information of TA system TA112853

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 4839..5470
• Replicon: plasmid pAt15955
• Accession: NZ_CP032919
• Organism: Agrobacterium tumefaciens strain 15955

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: At15955_RS23335
• Protein ID: WP_038496209.1
• Coordinates: 4839..5240 (-)
• Length: 134 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: At15955_RS23340
• Protein ID: WP_003519381.1
• Coordinates: 5240..5470 (-)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
At15955_RS23310	1221..2246	+	1026	WP_038496201.1	plasmid partitioning protein RepB	-
At15955_RS23315	2449..3663	+	1215	WP_038496203.1	replication initiation protein RepC	-
At15955_RS23325	3873..4166	-	294	WP_038496206.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	-
At15955_RS23330	4545..4763	+	219	WP_038497375.1	BrnA antitoxin family protein	-
At15955_RS23335	4839..5240	-	402	WP_038496209.1	tRNA(fMet)-specific endonuclease VapC	Toxin
At15955_RS23340	5240..5470	-	231	WP_003519381.1	antitoxin	Antitoxin
At15955_RS23350	6255..6395	-	141	WP_003518781.1	hypothetical protein	-
At15955_RS23355	6766..7536	-	771	WP_038496212.1	4-hydroxy-2-oxoheptanedioate aldolase	-
At15955_RS23360	7544..8326	-	783	WP_038496215.1	2-oxo-hepta-3-ene-1,7-dioic acid hydratase	-
At15955_RS23365	8346..9239	-	894	WP_038496218.1	intradiol ring-cleavage dioxygenase	-
At15955_RS23370	9485..10219	+	735	WP_038496221.1	GntR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..814493	814493

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (1-125)

Antitoxin

• Bacterial antitoxin of type II TA system, VapB (16-56)

Sequences

Toxin

Protein

• Length: 134 a.a.
• Molecular weight: 19739.68 Da
• Isoelectric Point: 5.5500

>T112853 WP_038496209.1 NZ_CP032919:c5240-4839 [Agrobacterium tumefaciens]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 402 bp

>T112853 NZ_CP032919:c5240-4839 [Agrobacterium tumefaciens]
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Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 11350.61 Da
• Isoelectric Point: 5.5500

>AT112853 WP_003519381.1 NZ_CP032919:c5470-5240 [Agrobacterium tumefaciens]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 231 bp

>AT112853 NZ_CP032919:c5470-5240 [Agrobacterium tumefaciens]
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