Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 928469..929075 Replicon chromosome
Accession NZ_CP032912
Organism Helicobacter pylori strain 13-A-EK8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag D4H18_RS04595 Protein ID WP_139522915.1
Coordinates 928469..928729 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag D4H18_RS04600 Protein ID WP_139522916.1
Coordinates 928710..929075 (-) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D4H18_RS04575 925110..925877 - 768 WP_000242349.1 ABC transporter ATP-binding protein -
D4H18_RS04580 925877..926857 - 981 WP_000921458.1 iron ABC transporter permease -
D4H18_RS04585 926850..927698 - 849 WP_139522914.1 SDR family oxidoreductase -
D4H18_RS04590 927838..928362 + 525 WP_001135604.1 acyl-CoA thioesterase -
D4H18_RS04595 928469..928729 - 261 WP_139522915.1 type II toxin-antitoxin system YafQ family toxin Toxin
D4H18_RS04600 928710..929075 - 366 WP_139522916.1 hypothetical protein Antitoxin
D4H18_RS04610 929918..932146 - 2229 WP_139522917.1 Hop family adhesin BabA -
D4H18_RS04625 933058..933320 - 263 Protein_864 hypothetical protein -
D4H18_RS04630 933287..933454 - 168 WP_139522918.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10157.93 Da        Isoelectric Point: 8.0619

>T112836 WP_139522915.1 NZ_CP032912:c928729-928469 [Helicobacter pylori]
VLKLNLKKSFQKDFDRLLLNGFDDSVLNEVILRKKEPLDPQFQDHALKGKWKPFRECHIKPDVLLVYLVKDDELILLRLG
SHSELF

Download         Length: 261 bp

>T112836 NZ_CP032912:c928729-928469 [Helicobacter pylori]
GTGTTGAAGCTCAATCTTAAAAAATCTTTTCAAAAAGATTTTGATAGATTACTTTTGAATGGGTTTGATGATAGCGTTTT
GAATGAAGTCATTCTAAGAAAAAAAGAACCGCTAGATCCACAATTTCAAGATCATGCCTTAAAAGGCAAGTGGAAACCTT
TTAGGGAATGCCACATCAAGCCTGATGTTTTGCTTGTGTACTTAGTGAAAGATGATGAACTGATTTTGTTAAGGTTAGGC
AGTCATAGCGAGTTGTTTTAA

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 14387.39 Da        Isoelectric Point: 8.9405

>AT112836 WP_139522916.1 NZ_CP032912:c929075-928710 [Helicobacter pylori]
MPNTTNKDYTKYSQRQLFNLMNKKEQEIEKLKRDRAYLEKKMAKELEKKDKGFTIKLEELNKILQEINKRANDCCFGHET
PNIQMQQAMRDVYNKETDLIVEDFSSYSNERKKALGVEAQS

Download         Length: 366 bp

>AT112836 NZ_CP032912:c929075-928710 [Helicobacter pylori]
ATGCCAAACACCACCAACAAAGATTACACAAAATACAGCCAAAGACAGCTTTTTAACCTCATGAATAAGAAAGAACAAGA
AATTGAAAAGCTAAAAAGGGATAGGGCGTATCTTGAAAAGAAAATGGCTAAAGAGCTAGAAAAAAAAGATAAAGGCTTCA
CTATCAAATTAGAAGAATTGAATAAAATCTTACAAGAGATCAACAAAAGAGCTAATGATTGTTGTTTTGGGCATGAAACC
CCAAACATTCAAATGCAACAAGCCATGAGAGATGTGTATAACAAAGAGACAGATTTGATTGTTGAGGATTTTTCTAGTTA
TAGCAATGAGAGAAAAAAGGCTTTAGGTGTTGAAGCTCAATCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References